Persian (Farsi) to English Science Biology (-tech,-chem,micro-)

OCTOPUS, a new method for predicting transmembrane
protein topology is presented and benchmarked using a dataset of
124 sequences with known structures. Using a novel combination
of hidden Markov models and artificial neural networks, OCTOPUS
predicts the correct topology for 94% of the sequences. In particular,
OCTOPUS is the first topology predictor to fully integrate modeling
of reentrant/membrane-dipping regions and transmembrane hairpins
in the topological grammar.