upstream/downstream processes

05:30 Feb 3, 2013

This question was closed without grading. Reason: Answer found elsewhere

English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals / Clinical Studies

English term or phrase: upstream/downstream processes

The manufacturing process of [xxxx] consists of upstream cell culture and downstream purification processes.
Cells used for production are free of contamination during the upstream process and allow high levels of safety and purity of the resulting [name of the drug] during the downstream process.

Terejimenez KudoZ activity Questions: 1219 (none open) (36 closed without grading) Answers: 1434
Local time: 14:37

Summary of answers provided

3 +2

procesos de elaboración/ de transformación

lorenab23

Summary of reference entries provided

Findings

lorenab23

Discussion entries: 5

Answers

11 hrs confidence:

peer agreement (net): +2

procesos de elaboración/ de transformación

Explanation:
Please see reference

lorenab23
United States
Local time: 12:37
Native speaker of:

English,

Spanish
PRO pts in category: 67

Reference comments

15 mins peer agreement (net): +4

Reference: Findings

Reference information:
El proceso íntegro de producción de un producto biotecnológico, de inicio a fin, suele conocerse como campaña y normalmente se divide en dos partes principales: elaboración (upstream) y transformación (downstream) .Los procesos de elaboración suponen la producción del producto proteico, con mayor frecuencia mediante la utilización de células (de microbios, insectos o mamíferos) que crecen en cultivo. Los procesos de transformación comprenden la recuperación, purificación, formulación y acondicionamiento del producto proteico.
Fase de elaboración (upstream)
La fase de elaboración comienza con las células que crean o diseñan los científicos para obtener el producto proteico [...]
Fase de transformación (downstream)
En la fase de transformación de la fabricación se aísla el producto proteico a partir de las células que lo produjeron.
http://www.amgen.es/doc3.php?op=profesionales_medicos2&ap=bi...

lorenab23
United States
Native speaker of:

English,

Spanish
PRO pts in category: 67

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