English to Portuguese Medical Medical (general)

Although malabsorption of bile salts may appear to be benign, it creates a cascade of consequences. If the ileum cannot "recycle" bile salts secreted into the GIT, hepatic production cannot maintain a sufficient bile salt pool or the secretions to emulsify lipids. The gastric and pancreatic lipases are capable of digesting some triglycerides to fatty acids and monoglycerides, but, without adequate micelle formation facilitated by bile salts, lipids are poorly absorbed. This can lead to malabsorption of fats and fat-soluble vitamins A, D, E, and K. In addition, malabsorption of fatty acids results in their combination with calcium, zinc, and magnesium to form fatty acid-mineral soaps, thus leading to their malabsorption as well. To compound matters, colonic absorption of oxalate is increased, leading to hyperoxaluria and increased frequency of renal oxalate stones. Relative dehydration and concentrated urine, which are common with ileal resections, further increase the risk of stone formation.