Please cross-check both references using the keywords "PEPSI" and "ICE".

It looks like isn't an acronymous, just ice. Anyway ICE is has a double meaning as acronymous In Case (of) Emergency, it could be this case.

[This answer was provided by the OP (Fathy), as per his client's feedback; please DO NOT rate nor approve this suggestion]

"[...] I could contact the client who confirmed that ICE means "Immune Effector Cell-associated Encephalopathy (ICE)", it is a scoring tool "ICE tool" which is used during the CAR-T Cell treatment for evaluating the symptoms the patient may have after CAR-T infusion. I really appreciate your time and your help with this
Thank you
FS" by user Fathy Shehatto @ 12:42 BST, 9 Jul 2019 in Discussion entry #4.

The urinary bladder is equipped with a reflex system including cold receptors of the bladder wall and having reflex pathways partly separate from the normal micturition reflex. The ice-water test involves cooling of the bladder wall with ice-cold saline solution. In the neurologically intact adult the test is negative. A positive test indicates overt or occult neuropathy. In this report, examples are given of patients presenting with bladder symptoms and a positive test but initially lacking signs of a neurological condition. During follow-up, various neurogenic diseases appeared. It is suggested that a positive icewater test may represent a negative prognostic urodynamic sign along with a potential risk for neurogenic disease to come.