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18:18 May 20, 2022
English to Spanish translations [PRO]
Medical - Medical: Health Care
English term or phrase: BR 5/9
Buenas tardes. Una consulta sobre una biopsia (estudios de cáncer de mama)

Biopsy results:

classic infiltrating lobular carcinoma grade 1, BR 5/9, no lymphovascular invasion, Er 90% PR 90% HER 2 SCORE 1

¿qué quiere decir "BR 5/9"? ¿Hay traducción en castellano?

Muchas gracias.
Diego Metzadour
Local time: 02:03


Summary of answers provided
5Grado histológico 5/9
Irene Playan Arana
Summary of reference entries provided
finding
liz askew
breast (BR) [5-9 years]
José Patrício

Discussion entries: 1





  

Answers


62 days   confidence: Answerer confidence 5/5
br 5/9
Grado histológico 5/9


Explanation:
Es el grado histológico. BR significa Bloom-Richardson, pero es una escala que se utilizaba anteriormente y que tiene otra puntuación. Habitualmente se utiliza la escala modificada de Nottingham o la de Scarff-Bloom-Richardson, que tienen puntuación de 3 a 9.
"La gradación Scarff-Bloom-Richardson se basa en la evaluación microscópica de patrones morfológicos y citológicos de las células tumorales, que incluye la formación de túbulos, pleomorfismo nuclear e índice mitótico. La suma de estos parámetros es la que califica a cada tumor de acuerdo con: grado I (3-5 puntos, bien diferenciado), grado II (6-7 puntos, moderadamente diferenciado) y grado III (8-9 puntos, pobremente diferenciado)."


    https://www.medigraphic.com/pdfs/circir/cc-2013/cc136g.pdf
Irene Playan Arana
Argentina
Specializes in field
Native speaker of: Native in SpanishSpanish
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Reference comments


34 mins peer agreement (net): +1
Reference: finding

Reference information:
Breast Cancer Diagnosis: Past, Present and Future - Agilent
https://www.agilent.com › whitepaper › public › 2...
PDF
ductal hyperplasia (ADH)/low-grade ductal carcinoma in situ (LG-DCIS) . ... breast cancer can be ****histologically graded as grade 1 (3-5/9)*****, grade 2 (6-7/9) ...

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Note added at 35 mins (2022-05-20 18:53:21 GMT)
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Comparative analysis of the histopathological and - SciELO
https://www.scielo.br › jbpml
PDF
by HZ Rocha · 2019 · Cited by 1 — Key words: ductal carcinoma of the breast; lobular carcinoma; ... Joint Committee on Cancer (UICC/AJCC)], ****histological grade or SBR***.

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Note added at 36 mins (2022-05-20 18:54:07 GMT)
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Scarff-Bloom-Richardson (SBR) grading: a pleiotropic marker ...
https://pubmed.ncbi.nlm.nih.gov › ...
by S Amat · 2002 · Cited by 132 — ****+The Scarff-Bloom-Richardson (SBR)**** grade, an important prognostic factor in breast cancer, was also associated with cell proliferation, a consistent ...

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Note added at 38 mins (2022-05-20 18:57:03 GMT)
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Breast Coding Guidelines
https://seer.cancer.gov › manuals › AppendixC
PDF
Bloom-Richardson (BR, Nottingham) scores 3-9 converted to grade (see conversion table above). 2.**** Bloom Richardson (BR)*** grade (low, intermediate, high).

liz askew
United Kingdom
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 178

Peer comments on this reference comment (and responses from the reference poster)
agree  Erzsébet Czopyk: Bloom-Richardson scores. You are great, Liz. My admiration and hugs from Budapest.
13 hrs
  -> Thank you!
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2 hrs
Reference: breast (BR) [5-9 years]

Reference information:
breast cancer in recurrence [5-9 years: rate ratio (RR) 0.90, 95% CI: 0.79-1.07; ≥10 years: RR

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Note added at 2 horas (2022-05-20 21:02:03 GMT)
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https://pubmed.ncbi.nlm.nih.gov/32527118/
The HRs and associated 95% confidence intervals (CIs) - https://www.jto.org/article/S1556-0864(21)02330-3/fulltext
HR, hazard ratio - https://www.jto.org/article/S1556-0864(21)02330-3/fulltext
Progesterone receptor-positive (PR-positive) breast cancer means that the cancer is using progesterone as fuel. According to BreastCancer.org, about 65 percent of ER-positive breast cancers are also PR-positive. - https://www.healthline.com/health/breast-cancer/er-positive-...
HER2 is a protein present on the outside of breast cells. - https://www.medicalnewstoday.com/articles/316789#what-is-her...
HER2 son las siglas de Factor de crecimiento epidérmico humano Receptor-type2 (Receptor-2 del factor de crecimiento epidérmico humano). - https://rochepacientes.es/cancer/mama/her2.html

José Patrício
Portugal
Native speaker of: Native in PortuguesePortuguese
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