trimming or trim diameter

Russian translation: *

19:08 Mar 11, 2019
English to Russian translations [PRO]
Medical - Medical: Instruments
English term or phrase: trimming or trim diameter
Термин представляет собой один из критериев качества ограничителя поршня (plunger stopper) медицинского шприца.

- No plunge rod cavity or non functioning thread
- External diameter out of specification (excluding trim)
- Non removable foreign matter (> 250 µm) on the contact surface, not common to the formulation
- Misorientation of plunger stoppers in the nest cavity (NSCF only)
- Visual molding defects - incomplete stoppers or splits between ribs (no leakage)
- Defective trimming or trim diameter > maximum outside diameter of stopper
Olga Firayner
Russian Federation
Local time: 19:42
Russian translation:*
Explanation:

дефекты обрезанного пояска уплотнителя и диаметр обрезки превышает номинальный диаметр уплотнителя (или т. н. "ограничителя" , а на самом деле пробки)
Stopper/pistons for syringes are well known in the prior art. Before the syringe is actuated, the stopper/piston performs the function of a stopper, isolating the fluid contained in the syringe body, and then during actuation, it transforms into a piston, pushing the fluid out of the syringe body, generally through a needle.
The stopper/piston thus needs to guarantee sealing, and it is thus generally made of rubber or some other similar elastomer. A drawback with that type of material relates to the risks of interaction between the material of the stopper/piston and the fluid to be dispensed, in particular during the storage stage, where such interaction might possibly spoil said fluid. In order to limit the risks of interaction, it has been proposed to coat the front surface of the stopper/piston, i.e. the surface in contact with the fluid while storing and while dispensing the fluid, with an appropriate coating. In particular, it has thus been proposed to have a thin film of ethylene tetrafluoroethylene (ETFE) on the front surface of the stopper/piston. That technique makes it possible to limit the risks of interaction between the material of the stopper/piston and the fluid. However, applying said film makes the manufacturing method more complex, and requires a cutting zone on the stopper/piston after molding, which is to be avoided.

https://sealing.datwyler.com/uploads/download/OCP-InJentle-f...
Despite the fact that the trim edge is
not intended to be a sealing rill, it is a significant
contributor to the frictional forces
for the ISO standard design.
http://www.ondrugdelivery.com/publications/Prefilled Syringe...
die trimming
https://www.compamed.de/profile_download/k-U2FsdGVkX19qohBpL...
Plunger stoppers
We offer you a wide range of plunger stoppers suitable for all our
Gx RTF® syringe types. Stoppers are made from pharmaceutical
elastomers and are available in different qualities: Bulk, ready-tosterilize
or ready-to-use. According to your needs, packaging options
vary from nested plunger stoppers to PE bags.
https://www.lonstroff.com/files/cto_layout/img/downloads/SRI...
4. Установка пробок
После того как готовые шприцы наполнены, необходимо установить пробки [рис. 9] и штоки.


--------------------------------------------------
Note added at 14 hrs (2019-03-12 10:00:48 GMT)
--------------------------------------------------

http://www.freepatentsonline.com/y2017/0368264.html
Selected response from:

hawkwind
Russian Federation
Local time: 02:42
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3см
Ksenia ILINSKA
3*
hawkwind
Summary of reference entries provided
hawkwind

  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5
см


Explanation:
неровный край/неправильная окружность или диаметр ограничителя поршня превышает наружный диаметр поршня

Ksenia ILINSKA
Ukraine
Local time: 19:42
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 44
Login to enter a peer comment (or grade)

14 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
*


Explanation:

дефекты обрезанного пояска уплотнителя и диаметр обрезки превышает номинальный диаметр уплотнителя (или т. н. "ограничителя" , а на самом деле пробки)
Stopper/pistons for syringes are well known in the prior art. Before the syringe is actuated, the stopper/piston performs the function of a stopper, isolating the fluid contained in the syringe body, and then during actuation, it transforms into a piston, pushing the fluid out of the syringe body, generally through a needle.
The stopper/piston thus needs to guarantee sealing, and it is thus generally made of rubber or some other similar elastomer. A drawback with that type of material relates to the risks of interaction between the material of the stopper/piston and the fluid to be dispensed, in particular during the storage stage, where such interaction might possibly spoil said fluid. In order to limit the risks of interaction, it has been proposed to coat the front surface of the stopper/piston, i.e. the surface in contact with the fluid while storing and while dispensing the fluid, with an appropriate coating. In particular, it has thus been proposed to have a thin film of ethylene tetrafluoroethylene (ETFE) on the front surface of the stopper/piston. That technique makes it possible to limit the risks of interaction between the material of the stopper/piston and the fluid. However, applying said film makes the manufacturing method more complex, and requires a cutting zone on the stopper/piston after molding, which is to be avoided.

https://sealing.datwyler.com/uploads/download/OCP-InJentle-f...
Despite the fact that the trim edge is
not intended to be a sealing rill, it is a significant
contributor to the frictional forces
for the ISO standard design.
http://www.ondrugdelivery.com/publications/Prefilled Syringe...
die trimming
https://www.compamed.de/profile_download/k-U2FsdGVkX19qohBpL...
Plunger stoppers
We offer you a wide range of plunger stoppers suitable for all our
Gx RTF® syringe types. Stoppers are made from pharmaceutical
elastomers and are available in different qualities: Bulk, ready-tosterilize
or ready-to-use. According to your needs, packaging options
vary from nested plunger stoppers to PE bags.
https://www.lonstroff.com/files/cto_layout/img/downloads/SRI...
4. Установка пробок
После того как готовые шприцы наполнены, необходимо установить пробки [рис. 9] и штоки.


--------------------------------------------------
Note added at 14 hrs (2019-03-12 10:00:48 GMT)
--------------------------------------------------

http://www.freepatentsonline.com/y2017/0368264.html

hawkwind
Russian Federation
Local time: 02:42
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 1952
Login to enter a peer comment (or grade)




Reference comments


14 hrs
Reference

Reference information:
http://www.standards.ru/document/4683421.aspx
http://archive.promoboz.com/n4_27/96-104.pdf
http://www.trworkshop.net/forum/viewtopic.php?f=63&t=49968
http://apps.who.int/medicinedocs/documents/s19638en/s19638en...
Depending on the type of container, closures may have different
shapes and sizes, e.g. stoppers for infusion or injection bottles or
plungers for prefilled syringes. A special design of stopper may also
be required for some pharmaceutical production processes such as
lyophilization.

hawkwind
Russian Federation
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 1952
Login to enter a peer comment (or grade)



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