Dec 5, 2018 05:13
5 yrs ago
English term
insecticidal leads
English to Portuguese
Science
Chemistry; Chem Sci/Eng
Spider toxins suggested suitable as insecticidal leads have immediate neurotoxic effects in the range of 10-100 pmol/g when injected intrathoracically; in comparison, the effect of α-1 at 1 µg/kg equals an amount of ~300 femtomol/g.
Proposed translations
(Portuguese)
4 +2 | candidatos a inseticida | Oliver Simões |
3 | ingredientes principais em inseticidas | Matheus Chaud |
3 | (compostos) inseticidas prospectivos | Paulo Marcon |
Proposed translations
+2
7 hrs
Selected
candidatos a inseticida
"Terminology
Lead compounds are sometimes called developmental candidates.[1] This is because the discovery and selection of lead compounds occurs prior to preclinical and clinical development of the candidate."(O grifo é meu.) - https://en.wikipedia.org/wiki/Lead_compound
O texto se refere a "suggested suitable" e "immediate neurotoxic effects", o que me leva a crer que se trata de um composto químico que está sendo usado como candidato a inseticida. Faz sentido de acordo com a explicação acima.
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Note added at 7 hrs (2018-12-05 12:43:00 GMT)
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Ou talvez: candidatos no desenvolvimento do/de inseticida
Lead compounds are sometimes called developmental candidates.[1] This is because the discovery and selection of lead compounds occurs prior to preclinical and clinical development of the candidate."(O grifo é meu.) - https://en.wikipedia.org/wiki/Lead_compound
O texto se refere a "suggested suitable" e "immediate neurotoxic effects", o que me leva a crer que se trata de um composto químico que está sendo usado como candidato a inseticida. Faz sentido de acordo com a explicação acima.
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Note added at 7 hrs (2018-12-05 12:43:00 GMT)
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Ou talvez: candidatos no desenvolvimento do/de inseticida
Example sentence:
... constataram uma eficiência como candidatos a inseticida e larvicida, além de retardar o desenvolvimento de Lobesia botrana...
4 KudoZ points awarded for this answer.
Comment: "Selected automatically based on peer agreement."
6 hrs
English term (edited):
insecticidal leads
ingredientes principais em inseticidas
Sugestão
7 hrs
(compostos) inseticidas prospectivos
Diria assim. "Leads" aqui está para "compound lead", que traduzi como prospectivo; uma substância promissora, ponto de partida, na pesquisa para uma finalidade qualquer.
"A lead compound (i.e. a "leading" compound, not to be confused with various compounds of the metallic element lead) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may nevertheless have suboptimal structure that requires modification to fit better to the target; lead drugs offer the prospect of being followed by back-up compounds." https://en.wikipedia.org/wiki/Lead_compound
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Note added at 7 hrs (2018-12-05 12:44:38 GMT)
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Errata: "lead compound", não "compound lead".
"A lead compound (i.e. a "leading" compound, not to be confused with various compounds of the metallic element lead) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may nevertheless have suboptimal structure that requires modification to fit better to the target; lead drugs offer the prospect of being followed by back-up compounds." https://en.wikipedia.org/wiki/Lead_compound
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Note added at 7 hrs (2018-12-05 12:44:38 GMT)
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Errata: "lead compound", não "compound lead".
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