Glossary entry (derived from question below)
English term or phrase:
bioavailability
Serbian translation:
biološka raspoloživost
Nov 17, 2009 16:59
14 yrs ago
3 viewers *
English term
bioavailability
GBK
English to Serbian
Medical
Medical: Pharmaceuticals
Definition from
USC Kidney Transplant Program:
a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc.
Example sentences:
Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. (Merck & Co., Inc. )
The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. (Informa plc )
Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. (US National Institutes of Health)
Proposed translations
(Serbian)
5 +2 | biološka raspoloživost | Mira Stepanovic |
4 | bioraspoloživost | Katarina Delic |
Change log
Nov 17, 2009 16:25: changed "Kudoz queue" from "In queue" to "Public"
Nov 17, 2009 16:59: changed "Stage" from "Preparation" to "Submission"
Nov 20, 2009 17:54: changed "Stage" from "Submission" to "Completion"
Proposed translations
+2
38 mins
Selected
biološka raspoloživost
Definition from
own experience or research:
Nivo, mera u kojoj se određeni primenjeni lek absorbuje i uključuje u biološke procese u telu.
Example sentences:
S i m p o z i j u m ‚‚Ispitivanje biološke raspoloživosti i biološke ekvivalentnosti lekova - regulatorni i praktični aspekti” (Agenc. za lekove i med. sredstva Srbije)
Sublingvalnom i rektalnom primenom postiže se bolja biološka raspoloživost, nego posle per os primene. (Farmaceutski fakultet, Beograd)
Koncentracije leka niže od očekivanih najčešće su rezultat slabe biološke raspoloživosti leka, njegove brže eliminacije u odnosu na očekivanu, povećanog volumena distribucije ili nepostignutog stanja ravnoteže (1,2,5). Alternativno praćenje imunosupresivnih (Medicinski fakultet, Niš)
4 KudoZ points awarded for this answer.
1 hr
bioraspoloživost
Definition from
Wikipedia:
U farmakologiji, bioraspoloživost se odnosi na udeo primenjene doze leka koji u neizmenjenom obliku dospeva u sistemsku cirkulaciju, i predstavlja jedan od osnovnih farmakokinetičkih parametara leka.
Example sentences:
Po definiciji, bioraspoloživost leka primenjenog intravenozno je 100%. (Wikipedia)
Something went wrong...