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00:01 Apr 28, 2009 |
Spanish to English translations [PRO] Medical - Medical (general) / parkinson | |||||||
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| Selected response from: benvolio29 (X) United States Local time: 01:19 | ||||||
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4 +3 | microelectrode recording technique |
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microelectrode recording technique Explanation: Microelectrode recording, or MER, is the most precise method of localizing the surgical site. Dr. Lenz pioneered the technique of recording activity from single neurons, as well as microstimulation with a custom designed microelectrode. The use of this technique has been endorsed by the Task Force on Surgery for Parkinson's Disease of the American Academy of Neurology Therapeutic and Technology Assessment Committee: Evaluation of Surgery for Parkinson's Disease. Dr Lenz has performed microrecordings in more than 800 cases of functional stereotactic procedures during the course of his training and practice. Lance Rowland, BS, a neurophysiology technician working with Dr Lenz, has a similar breadth of experience based on his research recordings with Dr Mahlon DeLong prior to his involvement with functional stereotactic cases. MER is used to further define the image-derived target. Because not all brains are the same, the information obtained from MER gives a more accurate target for final DBS placement. As the microelectrode passes along its trajectory, Dr Lenz and his neurophysiology team are able to visualize and hear the neuronal activity from different areas of the brain. The patient also is able to hear brain activity and discussions of the neurophysiology team throughout the surgery. As the microlectrode passes through the basal ganglia and the thalamus toward its final target (STN, GPi, Vim), we are able to identify specific structures based on unique patterns of spontaneous neuronal activity. Dr Lenz also moves specific joints in the upper and lower extremities of the patient in an attempt to modulate the activity in the sensorimotor portion of the final target. This allows us to create a map of the body within the desired target. Reference: http://www.neuro.jhmi.edu/DBS/mer.htm Reference: http://books.google.com/books?id=eMyB47CHYHoC&dq=microelectr... |
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