Glossary entry

English term or phrase:

Platelet glycoprotein GPIIb-IIIa complex

Arabic translation:

مركب بروتين-سكري يعمل على تجميع صفيحات الدم والتصاق غشاءاتها

Added to glossary by Hassan Al-Haifi (wordforword)
Aug 6, 2005 14:08
18 yrs ago
English term

Platelet glycoprotein GPIIb-IIIa complex

English to Arabic Medical Medical (general)
Sorry guys, no context. Just a term in a glossary. Should be related to Integrins of Cell adhesion molecules.

Discussion

I am flattered AMT, coming from a medical expert! Thanks.

Proposed translations

8 hrs
Selected

مركب بروتين-سكري يعمل على تجميع صفيحات الدم والتصاق غشاءاتها

It is an important protoplasmic agent found in blood platelets. Very important for preventing uncontrolled bleeding or hemorrages.

I went through many sources, namely ectaco, Webstetr;s Online and Merriam-Webster's Online. I lost the links because I had to jump from one definition to another.

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Note added at 8 hrs 35 mins (2005-08-06 22:43:12 GMT)
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It is of course a component of the platelet membranes.
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4 KudoZ points awarded for this answer. Comment: "Thanks worforword, and thank you all."
29 mins

لمنع التصاق الصفائح Platelet glycoprotein GPIIb-IIIa مركب

Platelet glycoprotein GPIIb-IIIa مركب
لمنع التصاق الصفيحات

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Note added at 2005-08-07 03:25:35 (GMT)
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Incubation of platelets with anti-GPIIb-IIIa showed inhibition of platelet adhesion at high shear rates.
For more detalis about platelet adhesion:
http://www.bloodjournal.org/cgi/content/abstract/72/1/82
Peer comment(s):

neutral Hassan Al-Haifi (wordforword) : I think you should check the function more closely. GPIIb-IIIa is an adehesion and aggegating agent of blood platelets, thus inducing blood to clot.
7 hrs
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24 mins

لويحات أو صفيحات البروتين السكري المركّب

لويحات أو صفيحات البروتين السكري المركّب نوع
GPIIb-IIa

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Note added at 40 mins (2005-08-06 14:48:22 GMT)
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أو مركّب البروتين السكري لغشاء الصفائح
Platelet membrane glycoprotein complex

http://www.james-arond-thomas.com/template.asp?articleid=313

Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. The complex is an integrin which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. A deficiency of GPIIb-IIIa results in Glanzmann\'s thrombasthenia.
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