Jun 4, 2017 17:10
6 yrs ago
16 viewers *
English term

wild type-sparing EGFR inhibitor

English to Spanish Medical Genetics
I'm traslating a chart about some cancer therapies. And I found this 'wild type-sparing EGFR inhibitor' as a note. I don't have much context to give you.

Target: EGFR (HER1/ERBB1)
Development Name(s): AP26113
Generic Name(s): brigatinib

Thanks!

Proposed translations

5 days
Selected

inhibidor de rfce que evita la forma nativa

rfce=receptor del factor de crecimiento epidérmico

el inhibidor brigatinib (que por cierto es una molécula pequeña, no una proteína, no un anticuerpo) evita el receptor nativo o de tipo salvaje. Se deduce que actúa sobre la forma mutante, pero la traducción no debe sobreinterpretar el original o estaríamos 'sobreescribiendo' el original.
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