Feb 9, 2010 13:57
14 yrs ago
English term
gene silencing
GBK
English to Danish
Science
Biology (-tech,-chem,micro-)
Definition from
MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent.
The process of gene silencing is important for the differentiation of many different types of cells.
Example sentences:
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
Proposed translations
(Danish)
| 4 +1 | Gene silencing |
Susmi Rosenthal
|
Change log
Feb 9, 2010 12:58: changed "Kudoz queue" from "In queue" to "Public"
Feb 9, 2010 13:57: changed "Stage" from "Preparation" to "Submission"
Feb 12, 2010 15:03: changed "Stage" from "Submission" to "Selection"
Proposed translations
+1
5 hrs
Gene silencing
Definition from
Techmedia A/S:
Meget simplificeret fungerer gene silencing ved at små dobbeltstrengede RNA molekyler (20-30 nukleobaser i længde) forhindrer matchende mRNA sekvenser i at blive translateret, hvilket i sidste ende resulterer i at det kodende gen »slukkes«.
Example sentences:
Mens forskere og virksomheder forsøger at realisere antisense-drømmen har et nyt koncept, kendt som gene silencing,14 baseret på siRNA (small interfering RNA), trådt ind i rampelyset. Gene silencing blev i sin tid opdaget ved et tilfælde. (Techmedia A/S)
Resistens mod kartoffelskimmel gennem "gene silencing" rettet mod Phytophthora infestans. (Fødevareministeriet)
Medinova har en lang række produkter inden for RNAi / Gene Silencing som repræsenterer flere forskellige teknikker. ... Short Hairpin RNA vektorer (shRNA) til gene silencing fra Origene. (Medinova Scientific A/S)
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