Glossary entry (derived from question below)
Dutch term or phrase:
hypercrien intestinaal epitheel
English translation:
hypersecretion from intestinal epithelial cells
Added to glossary by
Barend van Zadelhoff
Aug 25, 2020 09:12
3 yrs ago
25 viewers *
Dutch term
30+ years experience - accurate and fast
Native in: Dutch 
Works in: English to Dutch, Dutch to English, Flemish to English
hyperccrien
Dutch to English
Medical
Medical (general)
gastrointestinal diseases
This is part of a description of the result of a microbioscopic investigation and therefore I cannot give much context for confidentiality reasons: A referral is made to a "hypercrien intestinaal epitheel". None of my medical dictionaries have the word "hypercrien" (which may be Flemish) in them and when Googling it, I only got one result. Anyone out there ever heard of this before?
Proposed translations
(English)
| 4 +2 | hypersecretion |
Barend van Zadelhoff
|
| 3 +1 | hypercrine |
Marijke Singer
|
Change log
Sep 1, 2020 11:22: Barend van Zadelhoff Created KOG entry
Proposed translations
+2
4 hrs
Barend van Zadelhoff
Netherlands
Netherlands
Native in Dutch
Specializes in field
Netherlands
TR is the most intimate act of reading.
Native in: Dutch 
Works in: English to Dutch, Dutch to English, Dutch
Related KudoZ points
:
494
Dutch term (edited):
hypercrien
Selected
hypersecretion
hypersecretion from intestinal epithelial cells
Weinig hits voor 'hypercrine' (63 G-hits)
Waarschijnlijk vanuit het Frans.
hypercrinie
syn. hypersecretie.
https://www.betekenis-definitie.nl/hypercrinie
hypercrinie \i.pəʁ.kʁi.ni\ féminin
(Médecine) Augmentation plus ou moins considérable d’une secrétion.
https://fr.wiktionary.org/wiki/hypercrinie
Hypercrinie
Endocrinologie et métabolismes N. f. * hyper : du grec huper , au-dessus (anatomie) ou supérieur à la normale, en intensité ou en quantité ; * crinie, crinisme, crinique : du grec ekkrinein {-crine, -crinien, -crinie}, excréter. L'hypercrinie est la sécrétion excessive, d'une ou plusieurs glandes endocrines, c'est-à-dire hormonales, mais aussi les troubles qui en résultent. Dans la plupart des cas, cette pathologie est due au dysfonctionnement d'une ou plusieurs glandes qui peut alors provoquer des dérèglements en cascade. Le traitement peut consister en une hormonothérapie, en une chirurgie réparatrice des glandes (thyroïde par ex.) ou à des médicaments qui vont ralentir l'hypercrinie. Syn. : hyperendocrinie, hypercrinisme. L'adjectif hypercrinique qualifie une glande ou un tissu glandulaire dont la sécrétion est insuffisante ou inexistante.
https://www.dictionnaire-medical.net/term/39741,1,xhtml
intestinal epithelium
Cell types
Seven different cell types are produced by the stem cells that reside at the base of the crypts.[6] Each type matures according to its specific differentiation program as it migrates up and out of the crypt. Many of the genes necessary for differentiation into the different epithelial cell types have been identified and characterized (see this table). The cell types produced are: enterocytes, Goblet cells, enteroendocrine cells, Paneth cells, microfold cells, cup cells and tuft cells. Their functions are listed here:[7]
Enterocytes are the most numerous and function primarily for nutrient absorption. Enterocytes express many catabolic enzymes on their exterior luminal surface to break down molecules to sizes appropriate for uptake into the cell. Examples of molecules taken up by enterocytes are: ions, water, simple sugars, vitamins, lipids, peptides and amino acids.
Goblet cells secrete the mucus layer that protects the epithelium from the lumenal contents.
Enteroendocrine cells secrete various gastrointestinal hormones including secretin, pancreozymin, enteroglucagon among others. Subsets of sensory intestinal epithelial cells synapse with nerves[8], and are known as neuropod cells.[9]
Paneth cells produce antimicrobial peptides such as human beta-defensin.[10][11]
Microfold cells (commonly referred to as M cells) sample antigens from the lumen and deliver them to the lymphoid tissue associated with the mucosa (MALT). In the small intestine, M cells are associated with Peyer's patches.
Cup cells are a distinct cell type but with no known function.
Tuft cells play a part in the immune response.[12]
https://en.wikipedia.org/wiki/Intestinal_epithelium
Example for globet cells in the airways
Mucus hypersecretion from goblet cells add to the mess and blockage of airways
https://www.superiorhealthplan.com/content/dam/centene/Super...
--------------------------------------------------
Note added at 4 hrs (2020-08-25 14:02:11 GMT)
--------------------------------------------------
typo: globet --> goblet
--------------------------------------------------
Note added at 1 day 4 hrs (2020-08-26 13:57:06 GMT)
--------------------------------------------------
Waarom een probleem, Willemina?
Nederlands heeft een andere syntax dan Engels.
Bijvoeglijke naamwoorden kunnen bijwoorden worden, hele zinnen kunnen worden omgegooid, you name it.
Dat heet 'function shift' in de vertaalwetenschap.
Waar het om gaat in vertalen is dat de betekenis zo goed mogelijk wordt overgebracht.
'hypersecretion from intestinal epithelial cells' geeft goed weer, taalkundig, inhoudelijk en technisch, wat wordt vermeld in 'hypercrien intestinaal epitheel'
en 'hypocrine intestinal epithelium' is onacceptabel wat mij betreft.
Precies de reden waarom ik een alternatieve oplossing heb aangeboden.
--------------------------------------------------
Note added at 1 day 4 hrs (2020-08-26 14:09:32 GMT)
--------------------------------------------------
Ik zie nu dat je 'hypercrine' hebt veranderd in 'hypercrinic'.
Ook dat lijkt niet te werken.
Het is een 'false friend' op basis van het Frans.
Zowel 'hypercrine intestinal epithelium' als 'hypercrinic intestinal epithelium' lijken mij onacceptabel.
--------------------------------------------------
Note added at 1 day 5 hrs (2020-08-26 14:30:52 GMT)
--------------------------------------------------
Ik krijg in totaal 98 G-hits met 'hypercrinia' (onderaan pagina op 10 klikken).
In in verreweg de meeste gevallen daarvan wordt de term dan verklaard. :-)
En hoe zou je 'hypercrinia' dan willen inbouwen?
Als je heel goed zoekt tussen die 98 hits zie je dingen als:
... suppresses the inflammation and oedema of the mucous membrane with hypercrinia ...
intestinal epithelium with hypercrinia ?
en:
Important diagnostic microscopic features of CD are architectural abnormalities of the villi (irregularity and blunting or broadening), preserved mucin secretion or increased mucin production (hypercrinia) by epithelial cells, mucoid or pseudopyloric metaplasia, active chronic inflammation and the presence of granulomas.
http://www.med-info.nl/literatuur/Crohn_CU_IBS.pdf
increased mucin production (hypercrinia) by intestinal epithelial cells ?
--------------------------------------------------
Note added at 1 day 12 hrs (2020-08-26 22:12:08 GMT)
--------------------------------------------------
Belgisch artikel.
1
Department of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium;
2
Department of Pathology, University Hospital Gasthuisberg, Leuven,
Belgium; 3 Department of Gastroenterology, University Hospital
Gasthuisberg, Leuven, Belgium
https://onlinelibrary.wiley.com/doi/pdf/10.1034/j.1600-0854....
Het is 1 van de 42 G-hits voor 'hypercrinic'.
De vertaler vond het blijkbaar geen probleem.
Je zou dan uitkomen op:
hypercrinic intestinal epithelium (i.p.v. hypercrinic colonic epithelium)
Weinig hits voor 'hypercrine' (63 G-hits)
Waarschijnlijk vanuit het Frans.
hypercrinie
syn. hypersecretie.
https://www.betekenis-definitie.nl/hypercrinie
hypercrinie \i.pəʁ.kʁi.ni\ féminin
(Médecine) Augmentation plus ou moins considérable d’une secrétion.
https://fr.wiktionary.org/wiki/hypercrinie
Hypercrinie
Endocrinologie et métabolismes N. f. * hyper : du grec huper , au-dessus (anatomie) ou supérieur à la normale, en intensité ou en quantité ; * crinie, crinisme, crinique : du grec ekkrinein {-crine, -crinien, -crinie}, excréter. L'hypercrinie est la sécrétion excessive, d'une ou plusieurs glandes endocrines, c'est-à-dire hormonales, mais aussi les troubles qui en résultent. Dans la plupart des cas, cette pathologie est due au dysfonctionnement d'une ou plusieurs glandes qui peut alors provoquer des dérèglements en cascade. Le traitement peut consister en une hormonothérapie, en une chirurgie réparatrice des glandes (thyroïde par ex.) ou à des médicaments qui vont ralentir l'hypercrinie. Syn. : hyperendocrinie, hypercrinisme. L'adjectif hypercrinique qualifie une glande ou un tissu glandulaire dont la sécrétion est insuffisante ou inexistante.
https://www.dictionnaire-medical.net/term/39741,1,xhtml
intestinal epithelium
Cell types
Seven different cell types are produced by the stem cells that reside at the base of the crypts.[6] Each type matures according to its specific differentiation program as it migrates up and out of the crypt. Many of the genes necessary for differentiation into the different epithelial cell types have been identified and characterized (see this table). The cell types produced are: enterocytes, Goblet cells, enteroendocrine cells, Paneth cells, microfold cells, cup cells and tuft cells. Their functions are listed here:[7]
Enterocytes are the most numerous and function primarily for nutrient absorption. Enterocytes express many catabolic enzymes on their exterior luminal surface to break down molecules to sizes appropriate for uptake into the cell. Examples of molecules taken up by enterocytes are: ions, water, simple sugars, vitamins, lipids, peptides and amino acids.
Goblet cells secrete the mucus layer that protects the epithelium from the lumenal contents.
Enteroendocrine cells secrete various gastrointestinal hormones including secretin, pancreozymin, enteroglucagon among others. Subsets of sensory intestinal epithelial cells synapse with nerves[8], and are known as neuropod cells.[9]
Paneth cells produce antimicrobial peptides such as human beta-defensin.[10][11]
Microfold cells (commonly referred to as M cells) sample antigens from the lumen and deliver them to the lymphoid tissue associated with the mucosa (MALT). In the small intestine, M cells are associated with Peyer's patches.
Cup cells are a distinct cell type but with no known function.
Tuft cells play a part in the immune response.[12]
https://en.wikipedia.org/wiki/Intestinal_epithelium
Example for globet cells in the airways
Mucus hypersecretion from goblet cells add to the mess and blockage of airways
https://www.superiorhealthplan.com/content/dam/centene/Super...
--------------------------------------------------
Note added at 4 hrs (2020-08-25 14:02:11 GMT)
--------------------------------------------------
typo: globet --> goblet
--------------------------------------------------
Note added at 1 day 4 hrs (2020-08-26 13:57:06 GMT)
--------------------------------------------------
Waarom een probleem, Willemina?
Nederlands heeft een andere syntax dan Engels.
Bijvoeglijke naamwoorden kunnen bijwoorden worden, hele zinnen kunnen worden omgegooid, you name it.
Dat heet 'function shift' in de vertaalwetenschap.
Waar het om gaat in vertalen is dat de betekenis zo goed mogelijk wordt overgebracht.
'hypersecretion from intestinal epithelial cells' geeft goed weer, taalkundig, inhoudelijk en technisch, wat wordt vermeld in 'hypercrien intestinaal epitheel'
en 'hypocrine intestinal epithelium' is onacceptabel wat mij betreft.
Precies de reden waarom ik een alternatieve oplossing heb aangeboden.
--------------------------------------------------
Note added at 1 day 4 hrs (2020-08-26 14:09:32 GMT)
--------------------------------------------------
Ik zie nu dat je 'hypercrine' hebt veranderd in 'hypercrinic'.
Ook dat lijkt niet te werken.
Het is een 'false friend' op basis van het Frans.
Zowel 'hypercrine intestinal epithelium' als 'hypercrinic intestinal epithelium' lijken mij onacceptabel.
--------------------------------------------------
Note added at 1 day 5 hrs (2020-08-26 14:30:52 GMT)
--------------------------------------------------
Ik krijg in totaal 98 G-hits met 'hypercrinia' (onderaan pagina op 10 klikken).
In in verreweg de meeste gevallen daarvan wordt de term dan verklaard. :-)
En hoe zou je 'hypercrinia' dan willen inbouwen?
Als je heel goed zoekt tussen die 98 hits zie je dingen als:
... suppresses the inflammation and oedema of the mucous membrane with hypercrinia ...
intestinal epithelium with hypercrinia ?
en:
Important diagnostic microscopic features of CD are architectural abnormalities of the villi (irregularity and blunting or broadening), preserved mucin secretion or increased mucin production (hypercrinia) by epithelial cells, mucoid or pseudopyloric metaplasia, active chronic inflammation and the presence of granulomas.
http://www.med-info.nl/literatuur/Crohn_CU_IBS.pdf
increased mucin production (hypercrinia) by intestinal epithelial cells ?
--------------------------------------------------
Note added at 1 day 12 hrs (2020-08-26 22:12:08 GMT)
--------------------------------------------------
Belgisch artikel.
1
Department of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium;
2
Department of Pathology, University Hospital Gasthuisberg, Leuven,
Belgium; 3 Department of Gastroenterology, University Hospital
Gasthuisberg, Leuven, Belgium
https://onlinelibrary.wiley.com/doi/pdf/10.1034/j.1600-0854....
Het is 1 van de 42 G-hits voor 'hypercrinic'.
De vertaler vond het blijkbaar geen probleem.
Je zou dan uitkomen op:
hypercrinic intestinal epithelium (i.p.v. hypercrinic colonic epithelium)
Note from asker:
| The problem is that hypercrien is used as an adjective here: hypercrien intestinal epitheel. |
| Ben het helemaal met je eens. Bedankt voor al je informatie. |
| Hypercrinia wordt ook veel gebruikt. Zie Google. Ik wil om allerlei redenen graag zo dicht mogelijk bij de tekst blijven. |
| Nog wat tijd besteed aan onderzoek en ben deze website met dit wetenschappelijke artikel tegengekomen: https://onlinelibrary.wiley.com/doi/pdf/10.1034/j.1600-0854.2004.000000132.x Hierin wordt onder andere hypercrinic gebruikt in de volgende context: On the other hand, in 8 of them, the crypt epithelium was markedly hypercrinic, as well at the surface as at the base of the crypts. They also had a less pronounced bile acid malabsorption but a significant faster colonic transit time, correlating with the trough level of mycophenolic acid (MPA). Only four patients had a complete remission of the diarrhea within 4 months. Conclusions: Persistent afebrile diarrhoea in renal transplant recipients is characterized by erosive enterocolitis, which is of infectious origin in at least 60 %. In 40 % a secretory enterocolitis was documented with a marked hypercrinic colonic epithelium, but without identifiable infectious cause. Because of a significant correlation between the colonic transit time and plasma MPA trough levels, MMF may be suggested as possible cause. |
Peer comment(s):
| agree |
philgoddard
7 hrs
|
|
Thank you, Phil.
|
|
| agree |
Kitty Brussaard
: Ik zou gewoon bij je eerste voorstel blijven.
4 days
|
|
Dank je, Kitty. Het kan misschien beter, maar wat mij betreft ook de beste oplossing.
|
4 KudoZ points awarded for this answer.
Comment: "Many thanks!"
+1
19 mins
Marijke Singer
Spain
Spain
Native in English
Specializes in field
Spain
Technical translator with Math degree
Native in: English , Spanish
Works in: Dutch to English, Spanish to English, English to Spanish, and 3 more.
Related KudoZ points
:
23
hypercrine
-crine is a suffix as in endocrine. On https://europepmc.org/article/med/13902697 they state hypercrine tumor.
--------------------------------------------------
Note added at 35 mins (2020-08-25 09:48:02 GMT)
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I used the DuckDuckGo search engine and added "-hypercrime". DuckDuckGo does not "think" like Google does :-)
--------------------------------------------------
Note added at 1 day 1 hr (2020-08-26 11:05:04 GMT)
--------------------------------------------------
Hypercrinic sounds like a good compromise:
"... hypercrinic action, that is, it stimulates all the secretory functions"
A pdf from the British Journal of Ophthalmology (British Medial Journal)
--------------------------------------------------
Note added at 35 mins (2020-08-25 09:48:02 GMT)
--------------------------------------------------
I used the DuckDuckGo search engine and added "-hypercrime". DuckDuckGo does not "think" like Google does :-)
--------------------------------------------------
Note added at 1 day 1 hr (2020-08-26 11:05:04 GMT)
--------------------------------------------------
Hypercrinic sounds like a good compromise:
"... hypercrinic action, that is, it stimulates all the secretory functions"
A pdf from the British Journal of Ophthalmology (British Medial Journal)
Note from asker:
| Many thanks. This seems to be a very rare use of the word because I cannot find anything anywhere. |
Peer comment(s):
| agree |
Brent Sørensen
: if endocrien (NL) → endocrine (EN) it’s logical that hypercrien (NL) → hypercrine (EN)
32 mins
|
|
Thank you!
|
|
| neutral |
philgoddard
: I'm not convinced this word exists. As Barend says, it gets very few hits, though "hypercrinia" gets plenty. But DuckDuckGo is growing on me too!
11 hrs
|
Discussion