soluble scTCR-Fab antigen binding proteins

Russian translation: см.

06:06 Dec 28, 2021
English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: soluble scTCR-Fab antigen binding proteins
...soluble scTCR-Fab antigen binding proteins comprising TCR variable domains with different affinity-maturated CDRs and/or framework mutations.
...scTCR-Fab antigen binding proteins with scTCR variant I (SEQ ID NO:
cherepanov
Ukraine
Local time: 05:03
Russian translation:см.
Explanation:
растворимые (химерные) белки на основе одноцепочечного Т-клеточного рецептора (scTCR) и антиген-связывающего фрагмента (Fab) (иммуноглобулина).
Хотя идеология данного объекта мне непонятна, но нечто подобное в литературе описано:
https://journals.plos.org/plosone/article/file?id=10.1371/jo...
Finally, the cFab format, a TCR/antibody chimeric Fab (cFab)
fragment, was constructed by fusing Vα from the TCR to CH1 and the Vβ to CK (Fig 1A and detailed in S1E Fig) [23, 24].
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Marlin31
Russian Federation
Local time: 05:03
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3см.
Marlin31


  

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3 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
soluble sctcr-fab antigen binding proteins
см.


Explanation:
растворимые (химерные) белки на основе одноцепочечного Т-клеточного рецептора (scTCR) и антиген-связывающего фрагмента (Fab) (иммуноглобулина).
Хотя идеология данного объекта мне непонятна, но нечто подобное в литературе описано:
https://journals.plos.org/plosone/article/file?id=10.1371/jo...
Finally, the cFab format, a TCR/antibody chimeric Fab (cFab)
fragment, was constructed by fusing Vα from the TCR to CH1 and the Vβ to CK (Fig 1A and detailed in S1E Fig) [23, 24].

Marlin31
Russian Federation
Local time: 05:03
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 262
Grading comment
Спасибо
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