pharmacological augmentation
French translation: l\'ajout d\'une seconde molécule/d’un second antidépresseur
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| 11:38 Jul 23, 2019 |
| English to French translations [PRO] Medical - Medical: Pharmaceuticals / psychiatrie | |||||||
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|  Selected response from: liz askew United Kingdom Local time: 11:46 | ||||||
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| 4 +3 | l'ajout d'une seconde molécule |
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| 4 +1 | augmentation du nombre d'agents pharmacologiques utilisés |
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Answers
11 mins confidence: 
peer agreement (net): +1
peer agreement (net): +1augmentation du nombre d'agents pharmacologiques utilisés Explanation: AKA polypharmacy, association of different antidepressors "Due to these considerations, antidepressant polypharmacy is only recommended for patients with treatmentresistant depression who may benefit from the synergistic effect of employing medications that have different mechanisms of action. This rationale based on pharmacological augmentation is highlighted in the recommendations of the American Psychiatry Association’s Practice guideline for the treatment of patients with major depressive disorder. [4] ... In clinical practice, psychiatrists usually start with one antidepressant. If there is no benefit or the side effects are severe the clinician will change the treatment to another antidepressant. If there is partial benefit and the side effects are relatively mild there are three potential options: (a) increase the dose of the first medication; (b) change to another medication; or (c) augment the first medication with a second antidepressant with an alternative mechanism of action that should, theoretically, improve the treatment effect without seriously exacerbating the side effects." -------------------------------------------------- Note added at 11 mins (2019-07-23 11:49:59 GMT) -------------------------------------------------- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311109/ |
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24 mins confidence: peer agreement (net): +3
peer agreement (net): +3l'ajout d'une seconde molécule Explanation: Patients hospitalisés au Centre Hospitalier du ... - Semantic Scholar https://pdfs.semanticscholar.org/.../79b7bbb515ebc440b797843... Translate this page 24 Nov 2017 - dépressif majeur : modification du traitement antidépresseur entre l'entrée ...... L'ajout d'une seconde molécule ne peut être entrepris qu'après ... -------------------------------------------------- Note added at 26 mins (2019-07-23 12:04:48 GMT) -------------------------------------------------- Augmentation, in the context of the pharmacological management of psychiatry, refers to the combination of two or more drugs to achieve better treatment results. Examples include: Prescribing an atypical antipsychotic when someone is already taking a selective serotonin reuptake inhibitor for the treatment of depression.[1] Prescribing estrogen for someone already being treated with antipsychotics for the management of schizophrenia.[2] Giving an adenosine A2A receptor antagonist on top of existing treatment for Parkinson's disease.[3] |
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