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Services
Translation, Interpreting, Editing/proofreading
Expertise
Specializes in:
Medical: Cardiology
Medical: Dentistry
Also works in:
Medical (general)
Medical: Health Care
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Payment methods accepted
Money order
Portfolio
Sample translations submitted: 1
English to Portuguese: Increased Gastrointestinal Permeability and Gut Inflammation in Children with Functional Abdominal Pain and Irritable Bowel Syndrome General field: Medical Detailed field: Medical (general)
Source text - English Surveys suggest that 10% to 17% of children between the ages of 4 and 16 years meet the criteria for recurrent abdominal pain.1-3 It has been suggested that the term recurrent abdominal pain be replaced by the terms functional abdominal pain and irritable bowel syndrome (FAP/IBS).4,5 FAP/IBS in children bear many similarities to IBS in adults and may be precursors for IBS.6-8 Gastrointestinal (GI) permeability is increased in adults with IBS9,10; however, the
limited data in children are unclear. Similarly, a few studies report GI inflammation (ie, increased fecal calprotectin concentration) in adults with IBS.9 Little data are available
regarding calprotectin in children.11,12 To our knowledge no pediatric studies have sought to determine if changes in GI permeability or fecal calprotectin concentration relate to
FAP/IBS symptoms (eg, pain severity or frequency, stooling pattern).
The objectives of this study were to measure permeability throughout the GI tract (with sugar permeability tests) and gut inflammation (with fecal calprotectin) in a large
group of well characterized children with FAP/IBS and to compare the results to healthy children without GI complaints. We used a site-specific version of the GI permeability test to identify potential sites of abnormal mucosa. Calprotectin is a measure of inflammation
wherever it occurs in GI tract. Additionally, we sought to determine whether GI permeability or gut inflammation is related to FAP/IBS symptoms.
Translation - Portuguese Pesquisas sugerem que 10% a 17% das crianças entre as idades de 4 e 16 anos preenchem os critérios para dor abdominal recorrente.1-3 Foi sugerido que a dor abdominal recorrente seria substituída pela dor abdominal funcional e a síndrome do intestino irritável (DAF/SII).4,5 A DAF/SII em crianças possuem muitas semelhanças com o SII em adultos e podem ser precursores de SII.6-8
A permeabilidade gastrointestinal (IG) é aumentada em adultos com SII9,10; no entanto, os dados limitados em crianças não são claros. Da mesma forma, alguns estudos relatam inflamação GI (por exemplo, o aumento da concentração calprotectina fecal) em adultos com SII.9 Poucos dados estão disponíveis sobre a calprotectina em crianças.11,12 Para o nosso conhecimento, nenhum estudo pediátrico procurou determinar se as mudanças na permeabilidade GI ou concentração calprotectina fecal relacionam-se com os sintomas de DAF/SII (por exemplo, a intensidade da dor ou da frequência, e evacuação padrão).
Os objetivos deste estudo foram de medir a permeabilidade ao longo do trato gastrointestinal (com testes de permeabilidade do açúcar) e inflamação do intestino (com calprotectina fecal) em um grande grupo de crianças bem caracterizadas com DAF/SII e comparar os resultados com crianças saudáveis, sem queixas de GI. Usamos uma versão específica local do ensaio da permeabilidade GI para identificar locais potenciais de mucosa anormal. Calprotectina é uma medida de inflamação onde quer que ocorra no trato gastrointestinal. Além disso, buscamos determinar se a permeabilidade GI ou inflamação do intestino está relacionada aos sintomas de DAF/SII.
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Translation education
Bachelor's degree - UFPB
Experience
Years of experience: 21. Registered at ProZ.com: May 2011.
Dreamweaver, Frontpage, Microsoft Word, Powerpoint
Bio
Degree in Portuguese/English Language and Literature through the Federal University of Paraiba - Brazil, Certificate for Teaching English as a Second Language through the Univertity of Manitoba - Canada.
Knows Brazilian Portuguese, English and Spanish.
