housekeeping gene

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09:56 Apr 20, 2010
English to Serbian translations [PRO]
Medical - Genetics
Additional field(s): Biology (-tech,-chem,micro-)
English term or phrase: housekeeping gene
Definition from Wikipedia:
A housekeeping gene is typically a constitutive gene that is required for the maintenance of basal cellular function, and are found in all human cells.[1][2] Although some housekeeping genes are expressed at relatively constant levels(such as HSP90 and Beta-actin), other housekeeping genes may vary depending on experimental conditions.

Example sentence(s):
  • Here, the non-regulation of seven housekeeping genes (beta-tubulin, cyclophilin, actin, elongation factor 1-alpha (ef1alpha), 18S rRNA, adenine phosphoribosyl transferase (aprt), and cytoplasmic ribosomal protein L2) during biotic (late blight) and abiotic stresses (cold and salt stress) was tested on potato plants using geNorm software. National Center for Biotechnology Inform
  • An inherent assumption in the use of housekeeping genes is that expression of the genes remains constant in the cells or tissues under investigation. Although exceptions to this assumption are well documented, housekeeping genes are of value in fully characterized systems. American Physiological Society
  • The researchers propose that many other housekeeping genes in addition to HPRT may also be found to regulate important developmental pathways. MediLexicon International Ltd
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Summary of translations provided
4"domaćinski gen"
1jelena (X)


Translations offered

2 days 10 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
"domaćinski gen"

Definition from Alberts- Molecular biology of the cell:
To su geni koji kodiraju proteine koji su esencijalni za vijabilnost svake ćelije, te su stoga eksprimirani u svim tipovima ćelija u organizmu.

Example sentence(s):
  • Metodom tzv. hibridizacije DNA mogu se utvrditi razlike između DNA (redoslijeda baza) dviju vrsta. One su često vrlo male. U procjeni stvarne razlike treba imati na umu velik udio neaktivne DNA, te činjenicu da većinu aktivnih gena u genomu čine tzv. "domaćinski geni" (housekeeping genes), koji kodiraju za bjelančevine koje održavaju osnovnu strukturu i funkciju stanica, a one se minimalno razlikuju među vrstama. - Zavod za histologiju i embriologiju, Med  

Mada najčešće reč housekeeping ostaje na engleskom – ne prevodi se.
Primer rečenica:
Housekeeping geni- aktivni u svim ćelijama.
1jelena (X)
Local time: 05:32
Native speaker of: Native in SerbianSerbian
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