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Freelance translator and/or interpreter, Verified site user
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Source text - English Introduction
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and affects an estimated 180 million people worldwide.[1-3] Approximately 70% of acute HCV results in chronic infection of which more than 20% will develop liver cirrhosis. Further disease progression to hepatocellular carcinoma is observed in 5% of HCV-infected patients with cirrhosis.[4] The most common means of HCV transmission is through parenteral exposure.[5]
The current standard for antiviral treatment consists of combination therapy with peginterferon alfa and ribavirin for 24 or 48 weeks depending on viral genotype and is associated with a sustained virologic response (SVR) in approximately 46% to 80% of patients.[6,7] Although response rates are favourable, a number of studies indicate that HCV therapy is associated with several adverse effects of varying severity in many patients and can lead to cytokine-induced depression in approximately 20% to 40% of treated patients.[8-10] Finally, adverse events associated with HCV therapy, such as depression, can lead to noncompliance or even premature discontinuation.[11-14] This finding has led some experts to suggest that interferons not be given to HCV-infected patients who have preexisting psychiatric symptoms.[15]
Translation - French Introduction
L’infection par le virus de l’hépatite C (VHC) est une cause majeure de maladie hépatique chronique et affecte une population estimée à 180 millions de personne à travers le monde.[1-3] Environ 70 % des personnes atteintes d’une infection aiguë par le VHC évoluent vers une infection chronique parmi lesquelles plus de 20 % développent une cirrhose du foie. L’évolution de la maladie vers un carcinome hépatocellulaire est observée chez 5 % des patients infectés par le VHC ayant développé une cirrhose.[4] Le mode de transmission le plus courant du VHC est la voie parentérale.[5]
Actuellement, le traitement antiviral standard est un combiné de peginterféron alfa et de ribavirine pendant 24 ou 48 semaines en fonction du génotype viral ; il est associé à une réponse virologique soutenue (SVR) chez approximativement 46 à 80 % des patients.[6,7] Bien que les taux de réponse soient favorables, de nombreuses études montrent que le traitement anti-VHC est associé à plusieurs événements indésirables de gravité variable qui peuvent conduire à une dépression induite par la cytokine chez approximativement 20 à 40 % des patients traités.[8-10] Elles concluent que les événements indésirables associés au traitement anti-VHC, tels que la dépression, peuvent conduire à la non-observance ou même à l’interruption prématurée du traitement.[11-14] Ces conclusions ont conduit un certain nombre d’experts à suggérer que les interférons ne soient pas prescrits aux patients possédant des symptômes psychiatriques préexistants.[15]
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Experience
Years of experience: 24. Registered at ProZ.com: Oct 2007.
Adobe Acrobat, Catalyst, FrameMaker, IBM CAT tool, Idiom, Microsoft Excel, Microsoft Word, Passolo, Powerpoint, STAR Transit, Trados Studio, Wordfast
CV/Resume
CV available upon request
Bio
Translates into French
-> mother tongue Translates from:
English – fluent (worked in the UK and Pacific Islands)
Spanish – fluent (lived 6 years in Chile)
CV on requestMISSION
French Translator/Proofreader/Editor
Teaming with a large resource pool of French translator colleagues
UNIQUE SELLING PROPOSITION
1. Total service to the customer (7x24 hours availability)
2. Ability to deliver through teaming with equally experienced peers
3. Skilled in virtually all common CAT tools including Passolo, Transit, Trados, Idiom, WordFast, IBM Translation Manager
HIGHLIGHTS
• Translated more than 3 million words, general medical and software related documentation since 2001
• Translated more than 1,7 million words of diabete, cardiology, artroplasty, healthcare documentation (Medtronic, St Jude, Wright, etc.)
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Expertise