co-crystals

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00:54 Sep 4, 2020
English to Turkish translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
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Summary of translations provided
4 +1Ko-kristal
Amir Akbarpour Reihani


  

Translations offered


4 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
Ko-kristal


Definition from Wikipedia:
Ko-kristaller genellikle ne solvat ne de basit tuzlardan olmayan stokiyometrik bir orandakı iki veya daha fazla farklı moleküler yada iyonik bileşikten oluşan tek fazlı kristal maddeler olan katılardır.

Example sentence(s):
  • Bu çalışmada 3-hidroksibenzoik asit ile izonikotinamidin ko-kristali aseton-etanol çözeltisi içinde 1:1 oranında çözücü buharlaştırma yöntemi ile hazırlandı (Turkish). The co-crystal of 3-hydroxybenzoic acid and the isonicotinamide were prepared by solvent evaporation in a 1: 1 ratio in acetoneethanol solution (English). - Karaelmas Fen ve Mühendislik Dergisi  
  • Ko-kristallendirme, 1:1 molar oranda Pikrik asit ile 1-Bromopiren ve TNT ile 1-Bromopiren arasında çözücü buharlaştırma yöntemiyle hazırlandı ve ko-kristallerin yapısı tek kristal ve toz X ışını kırınımı, Kütle spektrometresi, Kızılötesi spektroskopisi ile karekterize edildi (Turkish). A 1:1 co-crystals of Picric Acid with 1-Bromopyrene and TNT with 1-Bromopyrene were prepared by a solvent evaporation method, and the structure of the co-crystals were determined by single-crystal and powder X-ray diffraction, Mass spectrometry, Infrared spectroscopy techniques (English). - Dergipark  
Amir Akbarpour Reihani
Local time: 00:50
Native speaker of: Native in Persian (Farsi)Persian (Farsi)
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Omer Dasbilek
3 days 3 hrs
  -> Teşekkürler Ömer Bey!
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