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vitamin k-dependent plasma glycoprotein

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00:54 May 17, 2020
English to Turkish translations [PRO]
COVID-19 - Science - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism
English term or phrase: vitamin k-dependent plasma glycoprotein
Definition from Science Direct:
Vitamin K–dependent proteins, synthesized in the liver, play a central role in blood coagulation through either procoagulant or anticoagulant mechanisms. The vitamin K–dependent protein family includes the zymogen procoagulant factors VII, IX, X, and prothrombin, and the anticoagulants protein C, protein S, and protein Z

Example sentence(s):
  • This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. National Center for Biotechnology Info.
  • Protein Z is a vitamin K-dependent glycoprotein isolated and characterized from human and bovine plasma. A cDNA coding for human protein Z has been obtained by the isolation of phage clones from a liver cDNA library and in vitro amplification of two other liver libraries. Research Gate
  • Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II, VII, IX, and X. This paper describes the purification of a hitherto unrecognized vitamin K-dependent glycoprotein from bovine plasma. The biosynthesis of this protein is interfered with by the vitamin K antagonist Dicoumarol. The JBC
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
5K vitaminine bağımlı plazma proteini
FATİH ORUÇ
3K vitaminine bağımlı plazma glikoprotein
Omer Dasbilek


  

Translations offered


10 mins   confidence: Answerer confidence 5/5
K vitaminine bağımlı plazma proteini


Definition from own experience or research:
K vitaminine bağımlı proteinler (KVBP)
Prokoagulan proteinler:
• Faktör II
• Faktör VII
• Faktör IX
• Faktör X
Antikoagulant proteinler:
• Protein C
• Protein S
• Protein Z

Example sentence(s):
  • Faktör X, aktivitesi K vitaminine bağımlı bir plazma proteini olup, pihtılaşma sisteminde çok önemli bir fonksiyonu vardır. - www.cshd.org.tr  
  • GLA modulü içeren proteinler K vitaminine bağımlı faktörler olarak tanımlanır - www.tphd.org.tr  
FATİH ORUÇ
Türkiye
Local time: 06:20
Native speaker of: Native in TurkishTurkish
PRO pts in category: 172
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12 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
K vitaminine bağımlı plazma glikoprotein


Definition from hacettepe.edu.tr:
Protein C (PC), K vitaminine bağımlı bir plazma proteinidir. Aktive Protein C (APC) protein C’den türeyen bir glikoproteindir. Trombin bağlı trombomodulin (T-TM) kompleksi tarafından bir aktivasyon peptitinin kırılmasıyla oluşur.

Example sentence(s):
  • Protrombin, K vitaminine bağımlı bir glikoprotein olup, molekül ağırlığı 7200 Dalton, plazma yarı ömrü ise 72 – 96 saat arasındadır. Protrombin iki bölgeden oluşmuştur. - istanbulsaglik.gov.tr  
  • K vitaminine bağımlı bir glikoprotein olan protein C, homeostazisin sağlanmasında önemli bir role sahiptir. - sdu.edu.tr  
  • Antitrombin III (anti-pıhtılaşma faktörü) Protein C (karaciğerde sentezlenen vitamin-K-bağımlı protein) Protein S içermez (K vitaminine bağımlı plazma glikoprotein) D-dimer (tromboz göstergesi) VA - Lupus antikoagülan (şüpheli antifosfolipid sendromu için) - ehealthtreats.com  
Omer Dasbilek
Türkiye
Local time: 06:20
Native speaker of: Native in TurkishTurkish
PRO pts in category: 60
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