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housekeeping gene

Swedish translation: Hushållningsgen

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:housekeeping gene
Swedish translation:Hushållningsgen

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09:55 Apr 20, 2010
English to Swedish translations [PRO]
Medical - Genetics
Additional field(s): Biology (-tech,-chem,micro-)
English term or phrase: housekeeping gene
Definition from Wikipedia:
A housekeeping gene is typically a constitutive gene that is required for the maintenance of basal cellular function, and are found in all human cells.[1][2] Although some housekeeping genes are expressed at relatively constant levels(such as HSP90 and Beta-actin), other housekeeping genes may vary depending on experimental conditions.

Example sentence(s):
  • Here, the non-regulation of seven housekeeping genes (beta-tubulin, cyclophilin, actin, elongation factor 1-alpha (ef1alpha), 18S rRNA, adenine phosphoribosyl transferase (aprt), and cytoplasmic ribosomal protein L2) during biotic (late blight) and abiotic stresses (cold and salt stress) was tested on potato plants using geNorm software. National Center for Biotechnology Inform
  • An inherent assumption in the use of housekeeping genes is that expression of the genes remains constant in the cells or tissues under investigation. Although exceptions to this assumption are well documented, housekeeping genes are of value in fully characterized systems. American Physiological Society
  • The researchers propose that many other housekeeping genes in addition to HPRT may also be found to regulate important developmental pathways. MediLexicon International Ltd
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Hushållningsgen
Definition:
"Hushållningsgen" syftar till en gen som utgör koden för ett protein som är ansvarigt för basala funktioner i cellen. Därför är hushållningsgenen ofta aktiv i samtliga celler i en organism.
Selected response from:

Johanna Shanir
Israel
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
5 +2Hushållningsgen
Johanna Shanir


  

Translations offered


7 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +2
Hushållningsgen


Definition from own experience or research:
"Hushållningsgen" syftar till en gen som utgör koden för ett protein som är ansvarigt för basala funktioner i cellen. Därför är hushållningsgenen ofta aktiv i samtliga celler i en organism.

Example sentence(s):
  • Ubiquitin är ett protein som i människan kodas av hushållningsgenen UBB. - Wikipedia  
  • Gengrupperna består av gener inom reproduktionen och två referensgrupper, hushållningsgener (så kallade ”housekeeping”, HK-gener) och gener inom immunförsvaret. - KTH  

Explanation:
Jag kunde inte omedelbart hitta en bra referens, men jag är väldigt säker på mitt svar.

Se även: http://sv.wikipedia.org/wiki/Housekeepinggen

När man mäter uttryck av en gen genom kvantitativ PCR, normaliserar man ofta RNA-mängderna av genen i fråga mot en hushållningsgen, eftersom man utgår ifrån att uttrycket av hushållningsgenen är stabilt oavsett biologiska behandlingar. Detta är försök jag själv har utfört otaliga gånger.
Johanna Shanir
Israel
Local time: 18:15
Native speaker of: Native in SwedishSwedish
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Linnéa Holmén
11 hrs
  -> Tack, Linnéa!
Yes  Angelica Kjellström
3 days 15 hrs
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