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co-crystals

Spanish translation: cocristales

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00:54 Sep 4, 2020
English to Spanish translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


This question is closed

Spanish translation:cocristales
Definition:
Los cocristales farmacéuticos son sólidos cristalinos constituidos por un IFA y un formador, los cuales se encuentran en la misma celda cristalina.
Selected response from:

Leda Roche
Uruguay
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
5 +3cocristales
Leda Roche


  

Translations offered


1 hr   confidence: Answerer confidence 5/5 peer agreement (net): +3
cocristales


Definition from Scientific Journal:
Los cocristales farmacéuticos son sólidos cristalinos constituidos por un IFA y un formador, los cuales se encuentran en la misma celda cristalina.

Example sentence(s):
  • Los cocristales farmacéuticos surgen como una posibilidad para mejorar las propiedades biofarmacéuticas y farmacotécnicas de un IFA (Ingrediente Farmacéutico Activo). - Scientific Journal  
  • Existen técnicas que forman con el principio activo sales, solvatos, polimorfos y, además, existen otras técnicas más novedosas como dispersiones sólidas amorfas y cocristales. - Scientific Thesis  
  • Una reciente guía de la FDA pone mayor atención en los cocristales como una herramienta en la formulación de formas farmacéuticas sólidas. - Scientific Journal  

Explanation:
Múltiples referencias en español
Leda Roche
Uruguay
Local time: 22:33
Native speaker of: Native in SpanishSpanish
PRO pts in category: 96

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Alberto Gómez Herrera: Perfect translation for it, widely used in Chemistry, Medicine and other sciences to describe co-crystallised (simultaneously crystallised) substances. Good job.
6 hrs
Yes  Monica Garcia: This is the correct translation of the term.
9 hrs
Yes  Robert Copeland
22 hrs
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