plasmid of human PD-L1

05:15 Apr 15, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: plasmid of human PD-L1
Iminodimethyl-λ6-sulfanone (374 mg, 4.02 mmol) was dissolved in acetonitrile (15 mL), bromoacetonitrile (576 mg, 4.82 mmol) and NaHCO3 (506 mg, 6.0 mmol) were then added, and the solution was heated to 88 °C and then reacted for 16 hrs. After the reaction was completed, the reaction solution was filtered, and the filtrate was concentrated, and separated by silica gel column chromatography (eluent: dichloromethane/methanol) to obtain 2-((dimethyl(oxo)-λ6-sulfaneylidene)amino)acetonitrile (212 mg, yield:
In addition, the plasmid of human PD-L1 was transfected into Raji cells to obtain a cell line capable of stably expressing PD-L1.
In some preclinical animal tumor models, it was also shown that blocking the signal pathway of PD-1/PD-L1 with a monoclonal antibody can enhance the immunoreaction and lead to immunoreactions to a series of histologically different tumors.
In Table 2 and Table 3:
Jurkat/NF-κB-luc/PD1 cells and Raji-PD-L1 cells were then cocultured and stimulated with OKT-3.
Maxim Polukhin
Local time: 22:50


Summary of answers provided
4плазмидная конструкция/вектор, содержащая/ий ген PD-L1 человека
Igor Andreev
4плазмида человеческого PD-L1
Oleksandr Mandzhos


  

Answers


2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
плазмида человеческого PD-L1


Explanation:
Более подробное описание "плазмида, содержащая последовательность человеческого PD-L1"

Примеры:
https://ru.ulfsciences.com/spla2-ib-induces-human-podocyte-a...
Плазмида человеческого PLA2R и пустые векторы были приобретены

https://edrid.ru/rid/219.017.d1c1.html
Экспрессионная плазмида мышиного PD-1 (в векторе pCMV6-Entry) была приобретена

Oleksandr Mandzhos
Ukraine
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 56

Peer comments on this answer (and responses from the answerer)
neutral  Igor Andreev: Более подробное описание - согласен, а так оба источника - более/менее подправленный машинный перевод (( // фильтровать - поиск золотых самородков всегда был нелегким )
2 hrs
  -> А что делать, МП наступает по всем фронтам...
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4 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
plasmid of human pd-l1
плазмидная конструкция/вектор, содержащая/ий ген PD-L1 человека


Explanation:
*

Igor Andreev
Local time: 22:50
Native speaker of: Native in RussianRussian
PRO pts in category: 435
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