hard endpoint.
Portuguese translation: Resultado objetivo/definitivo
| GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW) | ||||||
|---|---|---|---|---|---|---|
|
| 13:46 Jun 10, 2016 |
| English to Portuguese translations [PRO] Medical - Medical (general) / Technical | |||||||
|---|---|---|---|---|---|---|---|
|
| ||||||
|  Selected response from: Ana Costa Portugal Local time: 22:26 | ||||||
Grading comment
| |||||||
| Summary of answers provided | ||||
|---|---|---|---|---|
| 4 +1 | Resultado objetivo/definitivo |
| ||
| 4 | desfecho definitivo |
| ||
| 3 | desfechos clinicamente relevantes |
|
Answers
14 mins confidence: 
peer agreement (net): +1
peer agreement (net): +1Resultado objetivo/definitivo Explanation: The objectives of a trial must be stated in specific terms. Achieving objectives should not depend on observing a particular outcome of the trial, e.g. finding a difference in mean weight loss of exactly 2 kg, but in obtaining a valid result. For example, a randomized trial of 4 diets had as its objective, “To assess adherence rates and the effectiveness of 4 popular diets for weight loss and cardiac risk factor reduction.” (Dansinger et al. 2005). The endpoints (or outcomes), determined for each study participant, are the quantitative measurements required by the objectives. In the Dansinger weight loss study, the primary endpoint was identified to be mean absolute change from baseline weight at 1 year. In a cancer chemotherapy trial the clinical objective is usually improved survival. Survival time is recorded for each patient; the primary outcome reported may be median survival time or it could be five-year survival. Clinical trials typically have a primary objective or endpoint. Additional objectives and endpoints are secondary. The sample size calculation is based on the primary endpoint. Analysis involving a secondary objective has statistical power that is calculated based on the sample size for the primary objective. "Hard" endpoints are well-defined in the study protocol, definitive with respect to the disease process, and require no subjectivity. "Soft" endpoints are those that do not relate strongly to the disease process or require subjective assessments by investigators and/or patients. https://onlinecourses.science.psu.edu/stat509/book/export/html/31 |
| |||||||||||||||||||||||||||
Grading comment
| ||||||||||||||||||||||||||||
9 hrs confidence:
10 hrs confidence:
Login or register (free and only takes a few minutes) to participate in this question. You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy. KudoZ™ translation helpThe KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.
See also: Search millions of term translations Your current localization setting
English
Select a language Close search
| ||||||||||||||||||||||||||||
