gene silencing

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13:58 Feb 9, 2010
English to Malay translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. biotech-info.net
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
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Summary of translations provided
4penguncian gen
Roslindawati Haron


  

Translations offered


79 days   confidence: Answerer confidence 4/5Answerer confidence 4/5
penguncian gen


Definition from blog:
Menjadikan aktiviti gen yang tidak dikehendaki terhenti dengan mengaktifkan mekanisma yang akan mengganggu fungsi RNA

Example sentence(s):
  • Penguncian gen adalah sebahagian daripada modifikasi genetik dan merupakan teknik yang sangat berguna dalam membangunkan jenis tanaman baru dan mempunyai potensi besar dalam mengwal penyakit tumbuhan dan manusia. - The Malaysian Biotechnology Information  
  • Pembinaan genetic yang direka khas mengandungi intron yang diapit oleh pengulangan songsang (harpin swa-pelengkap) atau harpin-intron (ihpRNA) telah disahkan sebagai strategi yang berguna dalam menguncikan fungsi gen. - Malaysian Palm Oil Board  
  • Sesi yang dianjurkan Novartis Corp (M) Sdn. Bhd. juga dimaklumkan, penguncian gen akan membesar menjadi aspek bersepadu “pembangunan semula ubatan” pada abad ke 21. - sun2surf  
Roslindawati Haron
Malaysia
Local time: 01:17
Native speaker of: Native in MalayMalay
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