allostery

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10:01 Jan 7, 2010
English to Hebrew translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Genetics
English term or phrase: allostery
Definition from Biochemical Society:
Property of some proteins by which spatially separate functional sites in the molecule can communicate with each other via movements transmitted through the structure.

Example sentence(s):
  • Oligomerization enables cooperativity between multiple binding sites, a property referred to as allostery or allosteric regulation of enzymes (yet again, single polypeptide, multi-domain proteins show allosteric behavior). whatislife.com
  • The sequential model of allostery holds that subunits are not connected in such a way that a conformational change in one induces a similar change in the others. Thus all enzyme subunits need not exist in the same conformation. bio-medicine.org
  • It also follows that allostery is common and that homologous proteins can have different allosteric mechanisms. nature.com
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Summary of translations provided
5אלוסטריה
Odded Leon


  

Translations offered


115 days   confidence: Answerer confidence 5/5
אלוסטריה


Definition from own experience or research:
תופעה בה קשירת ליגנד לאתר מטרה על חלבון גורמת להשתנות מבנהו המרחבי של החלבון באופן המשנה את זמינותו של אתר מטרה אחר בחלבון לליגנד שלו או את פעילותו של אתר פעיל בחלבון.

Example sentence(s):
  • קואופרטיביות מתקיימת כאשר האפיניות לקשירה של מולקולה לליגנד שלה, משתנה כתלות בקישור של הליגנד אליה. קואופרטיביות היא מקרה פרטי של אלוסטריה - Wikipedia  
  • היקשרות המעכב לאתר האלוסטרי משנה את הקונפורמציה (את המבנה השלישוני) של האנזים כך שהמשיכה של הסובסטרט לאתר הפעיל קטנה. - Wikipedia  
Odded Leon
Israel
Local time: 04:09
Native speaker of: Hebrew
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