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  3. Medical: Pharmaceuticals

downstream processing

French translation: Traitement en aval

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00:55 Sep 23, 2020
English to French translations [PRO]
Science - Medical: Pharmaceuticals
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Medical (general)
English term or phrase: downstream processing
Definition from Pharma IQ:
Downstream Processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste. It is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g. insulin and human growth hormone), antibodies (e.g. infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds. Downstream processing is usually considered a specialized field in biochemical engineering.

Example sentence(s):
  • Downstream processing can also impact the distribution and levels of product-related impurities. Accurate monitoring of product-related impurities, including higher molecular weight and lower molecular weight species is critical for product safety. Science Direct
  • EasyMax chemical reactor is for fundamental parameter optimization in downstream processing method design and execution. METTLER TOLEDO
  • Furthermore, because chromatography can represent a significant portion of the cost of goods in downstream processing (DSP) operations, proper optimization of capacity and selectivity is required. BioPharm
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


This question is closed

French translation:Traitement en aval
Definition:
Ensemble des procédés de séparation, de concentration et de purification des anticorps monoclonaux après la culture des hybridomes en bioréacteur. Ensemble des procédés de séparation, de concentration et de purification des anticorps monoclonaux après la culture des hybridomes en bioréacteur.
Selected response from:

Chrislène Murat
France
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
4 +3Traitement en aval
Chrislène Murat


  

Translations offered


5 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
Traitement en aval


Definition from GDT:
Ensemble des procédés de séparation, de concentration et de purification des anticorps monoclonaux après la culture des hybridomes en bioréacteur. Ensemble des procédés de séparation, de concentration et de purification des anticorps monoclonaux après la culture des hybridomes en bioréacteur.

Example sentence(s):
  • Pour nettoyer (traitement en aval) un liquide composé de plusieurs ingrédients, on l’amène dans un process de chromatographie. Les ingrédients sont alors séparés grâce aux vitesses différentes auxquelles tous les liquides sont pompés dans la ligne en se basant sur les propriétés de flux différentes et les interactions d’intensité différente entre la phase stationnaire et la phase mobile des substances. - Société Burket  
  • Le traitement en aval (downstream processing) ●Les étapes ●séparation ●homogénéisation ●concentration ●purification - Université de Laval Québec  
Chrislène Murat
France
Local time: 01:04
Native speaker of: French
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Bridget Jean
2 hrs
  -> Merci
Yes  Dr Malick Mbengue
5 hrs
  -> Merci
Yes  Christine HOUDY
7 hrs
  -> Merci
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