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co-crystals

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00:55 Sep 4, 2020
English to Chinese translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
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GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
5共晶
Yining Wang


  

Translations offered


19 days   confidence: Answerer confidence 5/5
共晶


Definition from 《光谱学与光谱分析》2011年 �:
"晶体工程为晶体API的快速发展提供了除药物分子的同质异晶、成盐、水合化物和溶剂化物之外的第四个解决方案-共晶，成就了API的第四大种类-药物共晶。它之所以引起广大药学工作者的重视是因为共晶能使特定的药物分子的活性组分的晶体形式的数量大大增加。"

Example sentence(s):
  • “设计采用溶剂挥发法以一定的配比制备得到了六硝基六氮杂异伍兹烷（HNIW）和二硝基甲苯（DNT）的共晶,并针对晶体结构以及物相的改变,应用X射线粉末衍射（PXRD）、傅里叶变换红外光谱（FTIR）和拉曼光谱（Raman）相结合的方法,对共晶样品进行快捷而有效的表征。” - 《光谱学与光谱分析》2018年 �  
  • Research Progress on Cocrystal of Flavonoids 黄酮类化合物共晶的研究进展 - Journal of Modern Medicine & Health  
Yining Wang
United States
Local time: 10:58
Native speaker of: Native in ChineseChinese, Native in EnglishEnglish
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