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Inammatory Mediator Profiles

Chinese translation: 炎性介质特征

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Inammatory Mediator Profiles
Chinese translation:炎性介质特征
Entered by: Min Fang

10:49 May 26, 2020
English to Chinese translations [PRO]
Medical - Medical (general) / Medical term
English term or phrase: Inammatory Mediator Profiles
“The Role of Inammatory Mediator Profiles on Development of Airway Remodeling in Stable Asthma” 这里的“profiles"怎么理解？”是理解为”炎性介质特征“还是”炎性介质谱“或是其他的含义？ 感谢大家的帮助
Min Fang
China
炎性介质特征
Explanation:
炎性介质特征

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Note added at 1 hr (2020-05-26 12:34:36 GMT)
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炎性介质的特征/的特性


wenku.baidu.com › view
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王娇莉等［15］通过探究EB 和CVA 患者气道炎症细胞、 细胞因子和炎性介质的特征， 发现CVA 和哮喘诱导痰的LTC4 表达显著高于EB 组， 在EB 的PGE2 表达较CVA .

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Note added at 5 days (2020-06-01 05:45:36 GMT)
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320023/ Airway remodeling is generally quite broadly defined as any change in composition, distribution, thickness, mass or volume and/or number of structural components observed in the airway wall of patients relative to healthy individuals. However, two types of airway remodeling should be distinguished more clearly: (1) physiological airway remodeling, which encompasses structural changes that occur regularly during normal lung development and growth leading to a normal mature airway wall or as an acute and transient response to injury and/or inflammation, which ultimately results in restoration of a normal airway structures; and (2) pathological airway remodeling, which comprises those structural alterations that occur as a result of either disturbed lung development or as a response to chronic injury and/or inflammation leading to persistently altered airway wall structures and function. This review will address a few major aspects: (1) what are reliable quantitative approaches to assess airway remodeling? (2) Are there any indications supporting the notion that airway remodeling can occur as a primary event, i.e., before any inflammatory process was initiated? (3) What is known about airway remodeling being a secondary event to inflammation? And (4), what can we learn from the different animal models ranging from invertebrate to primate models in the study of airway remodeling? Future studies are required addressing particularly pheno-/endotype-specific aspects of airway remodeling using both endotype-specific animal models and “endotyped” human asthmatics. Hopefully, novel in vivo imaging techniques will be further advanced to allow monitoring development, growth and inflammation of the airways already at a very early stage in life.

Keywords: Asthma, Airway remodeling, Airway pathology

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Note added at 5 days (2020-06-01 06:57:52 GMT)
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这里说的是Inflammatory Mediator Profiles 在体内的某个病理过程中所起的作用，可见这个profiles不是指制图/制表/分析/分析之类的由研究人员所进行的活动，而是指 mediator 本身的特点。就像是在谈到病人的身高、体重之类的数据时，不能把身高/体重本身和测量身高体重这样的动作混肴起来。
Selected response from:

jyuan_us
United States
Local time: 05:14
Grading comment
不好意思，回复的有点晚。谢谢你的回答。我可能也更倾向于“特征”这个意思。
4 KudoZ points were awarded for this answer



Summary of answers provided
4炎性介质数据编译 / 炎性介质数据分析 / 炎性介质分析图 / 炎性介质分析表
Kiet Bach
4炎性介质特征
jyuan_us


Discussion entries: 1





  

Answers


1 day 7 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
inflammatory mediator profiles
炎性介质数据编译 / 炎性介质数据分析 / 炎性介质分析图 / 炎性介质分析表


Explanation:
profile: a formal summary or analysis of data, often in the form of a graph or table, representing distinctive features or characteristics. e.g. a biochemical profile of blood.

https://www.thefreedictionary.com/profile

https://www.atsjournals.org/doi/abs/10.1164/ajrccm-conferenc...

Kiet Bach
United States
Local time: 02:14
Specializes in field
Native speaker of: Native in ChineseChinese
PRO pts in category: 49
Login to enter a peer comment (or grade)

1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
inammatory mediator profiles
炎性介质特征


Explanation:
炎性介质特征

--------------------------------------------------
Note added at 1 hr (2020-05-26 12:34:36 GMT)
--------------------------------------------------

炎性介质的特征/的特性


wenku.baidu.com › view
Translate this page
王娇莉等［15］通过探究EB 和CVA 患者气道炎症细胞、 细胞因子和炎性介质的特征， 发现CVA 和哮喘诱导痰的LTC4 表达显著高于EB 组， 在EB 的PGE2 表达较CVA .

--------------------------------------------------
Note added at 5 days (2020-06-01 05:45:36 GMT)
--------------------------------------------------

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320023/ Airway remodeling is generally quite broadly defined as any change in composition, distribution, thickness, mass or volume and/or number of structural components observed in the airway wall of patients relative to healthy individuals. However, two types of airway remodeling should be distinguished more clearly: (1) physiological airway remodeling, which encompasses structural changes that occur regularly during normal lung development and growth leading to a normal mature airway wall or as an acute and transient response to injury and/or inflammation, which ultimately results in restoration of a normal airway structures; and (2) pathological airway remodeling, which comprises those structural alterations that occur as a result of either disturbed lung development or as a response to chronic injury and/or inflammation leading to persistently altered airway wall structures and function. This review will address a few major aspects: (1) what are reliable quantitative approaches to assess airway remodeling? (2) Are there any indications supporting the notion that airway remodeling can occur as a primary event, i.e., before any inflammatory process was initiated? (3) What is known about airway remodeling being a secondary event to inflammation? And (4), what can we learn from the different animal models ranging from invertebrate to primate models in the study of airway remodeling? Future studies are required addressing particularly pheno-/endotype-specific aspects of airway remodeling using both endotype-specific animal models and “endotyped” human asthmatics. Hopefully, novel in vivo imaging techniques will be further advanced to allow monitoring development, growth and inflammation of the airways already at a very early stage in life.

Keywords: Asthma, Airway remodeling, Airway pathology

--------------------------------------------------
Note added at 5 days (2020-06-01 06:57:52 GMT)
--------------------------------------------------

这里说的是Inflammatory Mediator Profiles 在体内的某个病理过程中所起的作用，可见这个profiles不是指制图/制表/分析/分析之类的由研究人员所进行的活动，而是指 mediator 本身的特点。就像是在谈到病人的身高、体重之类的数据时，不能把身高/体重本身和测量身高体重这样的动作混肴起来。

jyuan_us
United States
Local time: 05:14
Works in field
Native speaker of: Native in ChineseChinese
PRO pts in category: 362
Grading comment
不好意思，回复的有点晚。谢谢你的回答。我可能也更倾向于“特征”这个意思。
Login to enter a peer comment (or grade)



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