housekeeping gene

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09:54 Apr 20, 2010

English to Chinese translations [PRO]
Medical - Genetics
Additional field(s): Biology (-tech,-chem,micro-)

English term or phrase: housekeeping gene

Definition from Wikipedia:
A housekeeping gene is typically a constitutive gene that is required for the maintenance of basal cellular function, and are found in all human cells.[1][2] Although some housekeeping genes are expressed at relatively constant levels(such as HSP90 and Beta-actin), other housekeeping genes may vary depending on experimental conditions.

Example sentence(s):

Here, the non-regulation of seven housekeeping genes (beta-tubulin, cyclophilin, actin, elongation factor 1-alpha (ef1alpha), 18S rRNA, adenine phosphoribosyl transferase (aprt), and cytoplasmic ribosomal protein L2) during biotic (late blight) and abiotic stresses (cold and salt stress) was tested on potato plants using geNorm software. National Center for Biotechnology Inform
An inherent assumption in the use of housekeeping genes is that expression of the genes remains constant in the cells or tissues under investigation. Although exceptions to this assumption are well documented, housekeeping genes are of value in fully characterized systems. American Physiological Society
The researchers propose that many other housekeeping genes in addition to HPRT may also be found to regulate important developmental pathways. MediLexicon International Ltd

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4 +1

管家基因

Yulin Chang

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管家基因

Definition from 维基百科:
组织特异性基因和管家基因一类是维持细胞最基本生命活动的基因，是所有一切细胞都需具备的，由此译制基本生命活动所必需的结构和功能蛋白。这类基因称“House-keeping gene”，译为“管家基因”，它们与细胞分化关系不大。

Example sentence(s):

比较分析使用最广泛的4个标准管家摹因3-磷酸甘油醛脱氢酶、β-肌动蛋白、酸性核糖体磷蛋白P0及18S核糖体RNA在老年大鼠肝、肾、心、肺组织和大脑皮质中的表达情况. - 万方数据
常用的管家基因内参照试剂盒(定量PCR) - 丁香园
加利福尼亚大学分子遗传中心和圣地亚哥医学院的一项研究表明，一种叫HPRT的基因对促使人类原始细胞转变成大脑正常的神经细胞的过程具有重要的作用。这种代谢基因就是总所周知的管家基因（"housekeeping" genes）。 - 科学网

Yulin Chang
Taiwan
Local time: 08:52
Native speaker of:

Chinese

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