sub-myeloablative

Arabic translation: أقل جذًا للنخاع، باجتذاذ نقوي محدود

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)

English term or phrase:	sub-myeloablative
Arabic translation:	أقل جذًا للنخاع، باجتذاذ نقوي محدود
Entered by:	Alaa Zeineldine

20:16 Jul 27, 2015

English to Arabic translations [PRO]
Medical - Medical (general) / Stem Cell Translplants

English term or phrase: sub-myeloablative

Text:
"it may be necessary to use a less toxic chemotherapy protocol, called sub-myeloablative transplant to allow gradual engraftment of the donor cell’s with subsequent progressive replacement of the host’s own cells and immunity"

Background:
Stem cell transplants are preceded by a regime of high doses of chemotherapy and radiation to destroy stem cells in the patient's bone marrow; this allows for its replacement by stem cells from the donor bone marrow. In some cases, the risk of such preparation is too high for the patient, thus a sub-myeloablative transplant is applied in which the patient's marrow is not totally depleted.

In the term myeloablative, "myelo" means "related to marrow", "ablative" means "removal"

The term "sub-myeloablative" can be described as:
أقل جذّاً للنخاع

But is there a standard Arabic medical term for it?

Alaa Zeineldine KudoZ activity Questions: 228 (none open) (28 closed without grading) Answers: 1145 Egypt
Local time: 21:23

إعطاب نقوي غير كامل

Explanation:
Myelo-ablation brings the bone marrow generating capacity to Zero while sub-myelo-ablation would bring it down to 20% (for example).
Good-luck

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Note added at 21 hrs (2015-07-28 17:18:58 GMT)
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I would translate "sub-myeloablative transplant" as:
الزرع المصحوب بإعطاب نقوي غير كامل

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Note added at 21 hrs (2015-07-28 17:20:05 GMT)
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مع الحفاظ على المصطلح الإنجليزي بين قوسين

Selected response from:

Yasser El Helw
Egypt
Local time: 21:23

Grading comment

2 KudoZ points were awarded for this answer

Summary of answers provided

4 +1

دون تكاثري نقوي

TargamaT team

الخضوع لعملية زراعة بعد تلقي علاج كيميائي دون تدمير الخلايا الموجودة في نخاع العظم

Yaniv Moshkovitz

إعطاب نقوي غير كامل

Yasser El Helw

Answers

7 hrs confidence:

إعطاب نقوي غير كامل

Yasser El Helw
Egypt
Local time: 21:23
Specializes in field
Native speaker of:

Arabic,

English
PRO pts in category: 154

9 mins confidence:

peer agreement (net): +1

دون تكاثري نقوي

Explanation:
https://www.webteb.com/hematology/diseases/اللمفومة-اللاهودج...

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Note added at 10 mins (2015-07-27 20:26:55 GMT)
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http://forums.roro44.net/539926-5.html

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Note added at 13 hrs (2015-07-28 10:10:55 GMT)
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في الواقع اعتمدت على مراجع إنكليزية لفهم المصطلح ولكني أضفت مراجع عربية لتأكيد ورود ذكر المفردات في الحوليات العربية
http://www.ncbi.nlm.nih.gov/pubmed/20385248
https://clinicaltrials.gov/ct2/show/NCT00841724
https://books.google.ch/books?id=dbnk6C5EqFwC&pg=PT40&lpg=PT...

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Note added at 21 hrs (2015-07-28 17:29:12 GMT)
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أخي علاء، اعتمدت على الشرح الإنكليزي كما أسلفت، المرجع العربي وضعته لأني وجدت المصطلح موجود فيه

TargamaT team
France
Local time: 21:23
Native speaker of:

Arabic,

French
PRO pts in category: 712

Notes to answerer

Asker: I feel that the "webteb.com" page seems to have missed the point on this one. The adjective تكاثري almost reverses the meaning of "ablative".

1 day 10 hrs confidence:

الخضوع لعملية زراعة بعد تلقي علاج كيميائي دون تدمير الخلايا الموجودة في نخاع العظم

Explanation:
This resembles 'non-myeloablative transplant', in which the patient is given less intensified chemotherapy prior to surgery to facilitate the engraftment of donor cells. I think the term requires an explanation in Arabic and can't be translated literally.

Yaniv Moshkovitz
Israel
Local time: 22:23
Specializes in field
Native speaker of:

Hebrew
PRO pts in category: 24

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