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gain-of-function mutations

Iranian(Other) translation: جهش بدست آوردن کاربری

14:31 Oct 25, 2018
Iranian(Other) language (monolingual) [PRO]
Other / ...
Iranian(Other) term or phrase: gain-of-function mutations
Inherited erythromelalgia which sometimes is called IEM for short is in fact an intensive pain caused by gain-of-function mutations of peripheral sodium channels, in which warmth causes intensified pain. currently we have Little knowledge about its representation in brains.
Hasti Tari
Iran
Local time: 14:02
Selected answer:جهش بدست آوردن کاربری
Explanation:
جهش بدست آوردن کاربری

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Note added at 4 mins (2018-10-25 14:36:35 GMT)
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http://barsadic.com/W?eid=347347
Selected response from:

Seyedsina Mirarabshahi
Canada
Local time: 06:32
Grading comment
Thank you
4 KudoZ points were awarded for this answer



SUMMARY OF ALL EXPLANATIONS PROVIDED
5جهش بدست آوردن کاربری
Seyedsina Mirarabshahi
5جهشهای اکتساب عملکرد
Ahmadreza Niavarani, MD, PhD
4جهش بازیافتن عملکرد
Ehsan Kiani


  

Answers


4 mins   confidence: Answerer confidence 5/5
جهش بدست آوردن کاربری


Explanation:
جهش بدست آوردن کاربری

--------------------------------------------------
Note added at 4 mins (2018-10-25 14:36:35 GMT)
--------------------------------------------------

http://barsadic.com/W?eid=347347

Seyedsina Mirarabshahi
Canada
Local time: 06:32
Native speaker of: Native in Persian (Farsi)Persian (Farsi)
PRO pts in category: 889
Grading comment
Thank you
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6 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
جهش بازیافتن عملکرد


Explanation:
جهش بازیافتن عملکرد


    Reference: https://www.google.com/url?sa=t&source=web&rct=j&url=http://...
Ehsan Kiani
Native speaker of: Native in Persian (Farsi)Persian (Farsi)
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3 days 1 hr   confidence: Answerer confidence 5/5
جهشهای اکتساب عملکرد


Explanation:
مفهوم آن جهشهایی در ژن است که عملکرد تازه ای به پروتئین حاصل می دهد، مثل فعالتر شدن پروتئین یا قابلیت اتصال آن به اهداف تازه.

در مقابل آن جهشهای
loss of function
است که عملکرد طبیعی پروتئین کلا از بین می رود، چون جایگاه مهمی از پروتئین را دچار نقص میسازد یا صاخت آن را کلا منتفی مینماید

Ahmadreza Niavarani, MD, PhD
United Kingdom
Local time: 11:32
Native speaker of: Native in Persian (Farsi)Persian (Farsi)
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