14 mins confidence:  
50 mins confidence: peer agreement (net): +4 at the extremes of age
Explanation:
There are a number of valid ways of saying this, but this literal version is actually the one used in the source cited by the text you're dealing with, so you may wish to use it (I tend to, in this kind of situation, provided the expression is valid in itself). I'll conceal the sources in case of confidentiality issues.
Here's the Spanish context:
"Las erupciones por drogas ocurren en aproximadamente 2-3% de los pacientes hospitalizados y en más del 1% de los pacientes ambulatorios; son más frecuente en las mujeres que en los hombres y durante los extremos de la vida.1,2"
http://www.medigraphic.com/pdfs/cutanea/mc-2014/mc141_3j.pdf
This must be the actual text; note the typo "son más frecuente", also present in your quotation.
Source 2 cited here is:
A. K. Dubey et al., "Dermatological adverse drug reactions due to
systemic medications — a review of literature"
https://www.researchgate.net/profile/Mukhyaprana_Prabhu/publ...
In the abstract of this article it says:
"Extremes of age, female sex, previous history of ADRs and environmental factors are the major risk factors."
And in the conclusions:
"The various risk factors for ADRs are listed
below.
1. Age Although relatively few data are available, adverse events are more frequently encountered at the extremes of age."
It's a common expression in medical literature. There's always the problem of non-native English in such literature, but the following cases are all in texts by native speakers:
"Thymectomy is recommended as an option for patients with non-thymomatous generalized myasthenia, except at the extremes of age."
https://books.google.es/books?id=buvlpfGBH3YC&pg=PA423&lpg=P...
"In addition, many patients undergoing these interventions are frail, in poor health and at the extremes of age."
https://books.google.es/books?id=SOHi9lzUqz0C&pg=PA3&lpg=PA3...
"Clinical pharmacology in special populations: the extremes of age"
Sarah N. Hilmer and Madlen Gazarian
http://www.med.monash.edu.au/assets/docs/scs/psychiatry/psyc...
As I say, other things being equal I would be inclined to use the actual expression found in the source cited, rather than paraphrasing it.
| Charles Davis
Spain
Local time: 13:44
Native speaker of: English
PRO pts in category: 804
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| | Grading comment | Selected automatically based on peer agreement. |
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