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看不明白的一段话，Hochberg family

Chinese translation: Hochberg族系

02:11 Jan 9, 2013
English to Chinese translations [PRO]
Medical - Other
English term or phrase: 看不明白的一段话，Hochberg family
In order to strongly control the family-wise Type I error rate at 5%, hypotheses were tested sequentially based on the predefined hierarchy listed in the SAP (see Section 2.2.10.5, Multiplicity Adjustment, of the SAP included in appendix 9).While each step before the Hochberg procedures was conducted at the 5% significance level, the significance level within each Hochberg family was 2.5%, given that the overall alpha level was divided equally between the 2 families (defined by the dose of canagliflozin)

为了将总体Ⅰ类错误率控制在5%，根据SAP列出的预定义层次（见第附件9 SAP中第2.2.10.4节，多重性校正）进行序贯检验。由于Hochberg程序前的每一步均在5%显著性水平下进行，考虑到两个families之间的总a水平被均分（通过canagliflozin剂量定义），因此各Hochberg family显著性水平设为2.5%。
Fubin Che
Local time: 17:19
Chinese translation:Hochberg族系
Explanation:
family-wise error rate 也可翻译为 族系误差率

如此family翻成 族系 就好了

SAP： 统计参数计划书（statistical analysis plan）

总体α水平 即 总体显著性水平

Canagliflozin：强生糖尿病新药，译名不明

试译如下：
为了将第一类型总体错误率强有力地控制在5%，根据统计参数计划书（SAP）里罗列的预定义层次（见内含于SAP附件9中的第2.2.10.5节，多重性调整）对假设进行序贯检验。当Hochberg程序前的每一步均在5%显著性水平下进行时，假设两个族系之间的总体α水平被均分（由Canagliflozin剂量而定），则各Hochberg 族系内部的显著性水平为2.5%。
Selected response from:

Wen-zhe (Clyde) Ye
New Zealand
Local time: 21:19
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +1Hochberg族系
Wen-zhe (Clyde) Ye


Discussion entries: 1





  

Answers


4 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
看不明白的一段话，hochberg family
Hochberg族系


Explanation:
family-wise error rate 也可翻译为 族系误差率

如此family翻成 族系 就好了

SAP： 统计参数计划书（statistical analysis plan）

总体α水平 即 总体显著性水平

Canagliflozin：强生糖尿病新药，译名不明

试译如下：
为了将第一类型总体错误率强有力地控制在5%，根据统计参数计划书（SAP）里罗列的预定义层次（见内含于SAP附件9中的第2.2.10.5节，多重性调整）对假设进行序贯检验。当Hochberg程序前的每一步均在5%显著性水平下进行时，假设两个族系之间的总体α水平被均分（由Canagliflozin剂量而定），则各Hochberg 族系内部的显著性水平为2.5%。



    Reference: http://en.wikipedia.org/wiki/Familywise_error_rate
Wen-zhe (Clyde) Ye
New Zealand
Local time: 21:19
Native speaker of: Native in ChineseChinese, Native in EnglishEnglish
PRO pts in category: 8

Peer comments on this answer (and responses from the answerer)
agree  Joanna Chow
4 hrs
  -> 谢谢！
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