gleichmäßigen Wirkungsverlauf

English translation: stable time-activity profile

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase: gleichmäßigen Wirkungsverlauf
English translation:stable time-activity profile
Entered by: Lirka

14:31 Jun 18, 2012
German to English translations [PRO]
Medical - Medical: Pharmaceuticals
German term or phrase: gleichmäßigen Wirkungsverlauf
SPC (cholinesterase inhibitor):

"[Drug name] retard besitzt cholinerge Eigenschaften; es gehört zu den Hemmstoffen der Cholinesterasen. Unter diesen Substanzen zeichnet es sich durch gute Verträglichkeit, schonenden Wirkungseintritt, gleichmäßigen Wirkungsverlauf, lange Wirkungsdauer und allmähliches Abklingen der Wirkung aus. "

My attempt: "constant/steady time-effect profile"

Any corrections? Any better ideas ( more idiomatic?)?

Thanks!
Lirka
Austria
Local time: 23:53
stable action/time-effect profile
Explanation:
I found both action and time-effect profile and I couldn't see any significant difference.

Stable seems to me to meet the needs of the term and I found several hits for this.
Selected response from:

Vikki Pendleton
United Kingdom
Local time: 22:53
Grading comment
Thanks, Vikki. I went with 'activity profile', but I think time-effect is used as well.
4 KudoZ points were awarded for this answer



Summary of answers provided
4steady action profile
uyuni
3 +1stable action/time-effect profile
Vikki Pendleton
3steady activity profile
Carmen Lawrence
3stable pharmacokinetic profile
barbarameyer
3retains its effectiveness over time/ remains effective over time
Michael Martin, MA
2consistent effect
Wendy Streitparth


Discussion entries: 1





  

Answers


33 mins   confidence: Answerer confidence 2/5Answerer confidence 2/5
consistent effect


Explanation:
-

Wendy Streitparth
Germany
Local time: 23:53
Native speaker of: English
PRO pts in category: 12
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38 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
steady action profile


Explanation:
...insulin providing an ultra-long and *steady action profile*,...
http://www.novonordisk.com/include/asp/exe_news_attachment.a...

Specific assays to determine the level of the drug in the blood have ...... insulin component providing an ultra-long and *steady action profile*...
http://diabetesjournal.co.za/onlinejournal/vol9/vol9_issue1/...



uyuni
Local time: 23:53
Specializes in field
Native speaker of: Native in GermanGerman
PRO pts in category: 80
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48 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
stable action/time-effect profile


Explanation:
I found both action and time-effect profile and I couldn't see any significant difference.

Stable seems to me to meet the needs of the term and I found several hits for this.

Example sentence(s):
  • Degludec is an ultra-long-acting basal insulin analogue, which has a distinct slow absorption that provides a flat and stable action profile.

    Reference: http://www.foxbusiness.com/news/2012/06/08/novo-nordisk-insu...
Vikki Pendleton
United Kingdom
Local time: 22:53
Native speaker of: Native in EnglishEnglish
PRO pts in category: 4
Grading comment
Thanks, Vikki. I went with 'activity profile', but I think time-effect is used as well.

Peer comments on this answer (and responses from the answerer)
agree  Harald Moelzer (medical-translator)
16 hrs
  -> Thanks Harald
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1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5
steady activity profile


Explanation:
or 'even', gradual and balanced

Carmen Lawrence
Greece
Local time: 00:53
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 8
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5 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
gleichmäßiger Wirkungsverlauf
stable pharmacokinetic profile


Explanation:
So verstehe ich das.

barbarameyer
Native speaker of: Native in GermanGerman, Native in EnglishEnglish
PRO pts in category: 20
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2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
retains its effectiveness over time/ remains effective over time


Explanation:
The German is more euphemistic but I think that's what they mean..

--------------------------------------------------
Note added at 1 day21 mins (2012-06-19 14:53:19 GMT)
--------------------------------------------------

"giving stable levels of effect"

If this is the type of medication we're talking about, we may already have a ready-made description:

"BRUFEN RETARD tablets are specially formulated to allow the gradual release of active substance giving stable levels and a prolonged duration of effect over the dosage interval."

http://home.intekom.com/pharm/knoll/brufnret.html


    Reference: http://www.cardient.com/products/immuno/brm4-500mg
Michael Martin, MA
United States
Local time: 18:53
Native speaker of: Native in GermanGerman, Native in EnglishEnglish
PRO pts in category: 32
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