cross-Fab molecules cross-linked by recombinant human FAP
| 22:00 Mar 5, 2012 |
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| English to Spanish translations [PRO] Science - Biology (-tech,-chem,micro-) / Immunology | |||||||
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| Fab and FAP |
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| Discussion entries: 4 | |
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Answers
22 mins confidence: 
| cross-fab molecules cross-linked by recombinant human fap fragmento de unión al/los antígeno /antígenos (o simplemente fragmento FAB) Explanation: for starters -------------------------------------------------- Note added at 23 mins (2012-03-05 22:24:07 GMT) -------------------------------------------------- further help: Diccionario www.uco.es/grupos/...molecular/.../diccionario.ht... - Translate this page AGRETOPO: porción del antígeno que interacciona con la molécula de HLA. .... Fab (abrev. de fragmento de unión al antígeno): fragmento de una molécula de ... limitado solo a este antígeno o a otro que reaccione con este de forma cruzada. |
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15 hrs confidence:
| cross-fab molecules cross-linked by recombinant human fap moléculas Fab reticuladas que han sido reticuladas mediante FAP humano reticulante Explanation: moléculas Fab reticuladas cuya reticulación se produjo mediante FAP humano reticulante |
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Reference comments
15 mins |
| Reference: Fab and FAP Reference information: www.nature.com/onc/journal/v20/n30/full/1204558a.html Using antagonistic antigen-binding fragment (Fab) preparations of ... sTRAIL can be readily converted into a fully signal competent memTRAIL-like molecule, i.e. a ... Apoptosis induced by cross-linked sTRAIL in Jurkat cells was completely ... tumor stroma marker fibroblast activation protein (FAP) (Garin-Chesa et al., 1990). -------------------------------------------------- Note added at 20 mins (2012-03-05 22:21:12 GMT) -------------------------------------------------- http://en.wikipedia.org/wiki/Antibody CDRs, Fv, Fab and Fc Regions Some parts of an antibody have unique functions. The arms of the Y, for example, contain the sites that can bind two antigens (in general identical) and, therefore, recognize specific foreign objects. This region of the antibody is called the *******Fab (fragment, antigen binding)****** region. It is composed of one constant and one variable domain from each heavy and light chain of the antibody.[21] The paratope is shaped at the amino terminal end of the antibody monomer by the variable domains from the heavy and light chains. The variable domain is also referred to as the FV region and is the most important region for binding to antigens. More specifically, variable loops of β-strands, three each on the light (VL) and heavy (VH) chains are responsible for binding to the antigen. These loops are referred to as the complementarity determining regions (CDRs). The structures of these CDRs have been clustered and classified by Chothia et al. [22] and more recently by North et al.[23] In the framework of the immune network theory, CDRs are also called idiotypes. -------------------------------------------------- Note added at 21 mins (2012-03-05 22:22:02 GMT) -------------------------------------------------- http://www.proz.com/kudoz/english_to_spanish/medical:_pharma... fragment antigen binding (Fab) Spanish translation: fragmento de unión al/los antígeno /antígenos (o simplemente fragmento FAB) Entered by: Diego Cruz M.D. |
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