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  3. Medical (general)

浸潤性腫瘤の内部

English translation: inside the infiltrative mass

02:30 Jun 12, 2011
Japanese to English translations [PRO]
Medical - Medical (general)
Japanese term or phrase: 浸潤性腫瘤の内部
Sentence: 間質浸潤が起こり浸潤性腫瘤を形成しても、浸潤性腫瘤の内部や浸潤性腫瘤からかなり離れた乳管にまで乳癌の乳管内進展が拡大している場合がある。

I am not sure how to interpret the section "浸潤性腫瘤の内部や浸潤性腫瘤からかなり離れた乳管にまで乳癌の乳管内進展が拡大している場合がある"

Is it ok to interpret it as:
浸潤性腫瘤の内部まで乳癌の乳管内進展が拡大している場合がある and
浸潤性腫瘤からかなり離れた乳管にまで乳癌の乳管内進展が拡大している場合がある

What I don't understand here is how 乳癌の乳管内進展 (intraductal spread of breast cancer) can spread to the 浸潤性腫瘤の内部?

Or am I interpreting this sentence wrong, and I should treat "浸潤性腫瘤の内部や浸潤性腫瘤" as one item? I considered this, but could not understand the reason for distinguishing between 浸潤性腫瘤の内部 and 浸潤性腫瘤.
Joss Ky
Australia
Local time: 14:11
English translation:inside the infiltrative mass
Explanation:
To understand this, we should think about the pathology. Firstly, the breast has 3 major tissues: duct, lobule and interstitium. Secondly, BC has a variety of pathological types: intraductal carcinoma, infiltrating ductal carcinoma, medullary carcinoma, mucinous carcinoma, tubular carcinoma, lobular carcinoma in situ, infiltrating lobular carcinoma, inflammatory breast cancer and Paget's disease.

This sentence seems to describe carcinomas originated from ductal tissue, which can infiltrate the interstitium (stroma). In that case, the original ductal carcinoma is surrounded by infitrative mass, so we can see ductal spread inside the infitrative mass, and of course remote ducts.

For your reference, in this case, we should use the term 'infiltration' instead of 'invasion' (these are different) AND we'd better use the term 'mass' instead of 'tumor' (to avoid confusion breat cancer per se). We can use interstitium or stroma for 間質, but stroma is generally used in clinical settings.
Selected response from:

Jason Kang
Canada
Local time: 20:41
Grading comment
Thank you nakcl!
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +2inside the infiltrative mass
Jason Kang
4 +1inside the invasive tumor
Carlis Hsu


Discussion entries: 1





  

Answers


5 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
inside the invasive tumor


Explanation:
Although.....derived from stromal invasion, intraductal progression of breast cancer is also possible in the ducts inside the invasive tumor or those considerably remote therefrom.

Carlis Hsu
United States
Local time: 23:41
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in ChineseChinese
PRO pts in category: 41
Notes to answerer
Asker: Thank you Carlis. I picked nakcl's answer because the explanations he provided helped me. But your answer was just as good.


Peer comments on this answer (and responses from the answerer)
agree  Mami Yamaguchi
5 hrs
Login to enter a peer comment (or grade)

13 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +2
inside the infiltrative mass


Explanation:
To understand this, we should think about the pathology. Firstly, the breast has 3 major tissues: duct, lobule and interstitium. Secondly, BC has a variety of pathological types: intraductal carcinoma, infiltrating ductal carcinoma, medullary carcinoma, mucinous carcinoma, tubular carcinoma, lobular carcinoma in situ, infiltrating lobular carcinoma, inflammatory breast cancer and Paget's disease.

This sentence seems to describe carcinomas originated from ductal tissue, which can infiltrate the interstitium (stroma). In that case, the original ductal carcinoma is surrounded by infitrative mass, so we can see ductal spread inside the infitrative mass, and of course remote ducts.

For your reference, in this case, we should use the term 'infiltration' instead of 'invasion' (these are different) AND we'd better use the term 'mass' instead of 'tumor' (to avoid confusion breat cancer per se). We can use interstitium or stroma for 間質, but stroma is generally used in clinical settings.

Jason Kang
Canada
Local time: 20:41
Specializes in field
Native speaker of: Native in KoreanKorean
PRO pts in category: 157
Grading comment
Thank you nakcl!

Peer comments on this answer (and responses from the answerer)
agree  Mami Yamaguchi: Indeed,infiltrative (infiltration) is more appropriate here,I think.
8 hrs
  -> Thanks!
agree  Soonthon LUPKITARO(Ph.D.)
8 hrs
  -> Thanks!
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