derivatized with an adipic hydrazide spacer

Russian translation: получают производное со спейсером, гидразидом адипиновой кислоты

20:10 Dec 10, 2007
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals / immunology
English term or phrase: derivatized with an adipic hydrazide spacer
Это процесс получения конъюгатной вакцины против Haemophilus influenzae типа b.

The Hib polysaccharide is produced from Haemophilus influenzae type b strain 760705. The polysaccharide is generated by fermentation and purified by a series of precipitation and ultrafiltration steps. The purified polysaccharide is activated with cyanogens bromide, and derivatized with an adipic hydrazide spacer and then covalently bound to carrier protein Tetanus Toxoid.
Olena Kushnerenko
Ukraine
Local time: 22:13
Russian translation:получают производное со спейсером, гидразидом адипиновой кислоты
Explanation:
Т.е. полисахарид присоединяют к белку токсоида через разделитель (или мостик), которым является гидразид адипиновой кислоты. Но спейсер стало уже почти русским словом.
Selected response from:

Pavel Venediktov
Russian Federation
Local time: 23:13
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3получают производное со спейсером, гидразидом адипиновой кислоты
Pavel Venediktov


  

Answers


54 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
получают производное со спейсером, гидразидом адипиновой кислоты


Explanation:
Т.е. полисахарид присоединяют к белку токсоида через разделитель (или мостик), которым является гидразид адипиновой кислоты. Но спейсер стало уже почти русским словом.

Pavel Venediktov
Russian Federation
Local time: 23:13
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 1149
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