This site uses cookies. Some of these cookies are essential to the operation of the site, while others help to improve your experience by providing insights into how the site is being used. For more information, please see the ProZ.com privacy policy.
Cookie settings
  1. KudoZ™ Top
  2. English to Chinese
  3. Biology (-tech,-chem,micro-)

abasic dSpacer

Chinese translation: 无碱基间隔基 (dSpacer)

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:abasic dSpacer
Chinese translation:无碱基间隔基 (dSpacer)
Entered by: ysun

00:05 Oct 7, 2005
English to Chinese translations [PRO]
Medical - Biology (-tech,-chem,micro-)
English term or phrase: abasic dSpacer
Text:
"The modified oligonucleotides has the Formula I, wherein each of Z1, Z2, and Z3 is independently any sequence 0 to 12 nucleotides long which optionally includes a non-nucleotidic linker or abasic dSpacer."

Thank you in advance!
ysun
United States
Local time: 00:16
无碱基位点
Explanation:
dSpacer据我理解就是无碱基位点. Abasic不加也可以,也有用dSpacer (Abasic site)表示.请见 http://usa.eurogentec.com/code/en/page_02.asp?Page=58 中那个dSpacer是没有含氮的碱基的.


--------------------------------------------------
Note added at 2 hrs 24 mins (2005-10-07 02:29:29 GMT)
--------------------------------------------------

谢谢信任！我对这方面也没有什么特别的研究。只是据我知道，这里所谓位点是核酸链中的一个核苷酸位点。SPACER实际上就是基因间没有什么生物作用的核酸片段。核苷酸为核酸的基本单位，由氮碱、核糖和磷酸构成。从我上面给出的链接中的图可看到除DSPACER以外的SPACER都是由几个核苷酸组成的。而这个DSPACER特殊，只有一个位点，没有氮碱，甚至没有磷酸化（这可能也是显示其结构图的原因），故不能称之为核苷酸位点或核苷位点。也可能在核酸链中有的基因之间只有这么一个DSPACER，使它们之间有间隔。我不是专门研究这一方面的，现在也比较忙，有偏差之处，请指教。你也可以译作“无碱基间隔”，或后面再加上一个括号内说明这是“无碱基位点”
。仅供参考。


--------------------------------------------------
Note added at 4 hrs 20 mins (2005-10-07 04:25:05 GMT)
--------------------------------------------------

Hi Yueyin, I guess the "d" might mean"deformed" .

--------------------------------------------------
Note added at 2005-10-08 03:32:18 (GMT)
--------------------------------------------------

I noticed \"non-nucleotidic linker\" in your context, which is exactly what I meant in my explanation for \"这个DSPACER特殊，只有一个位点，没有氮碱，甚至没有磷酸化（这可能也是显示其结构图的原因），故不能称之为核苷酸位点或核苷位点\". From your context, the dSPACER is not singly between gerns. Rather, it is among the sequence of SPACERs, which are 0 to 12 nucleotides long. I am sorry for not reading your context carefully.
Selected response from:

Jianming Sun
Local time: 13:16
Grading comment
Jianming,

The link and explanations you provided did help me get a better understanding about dSpacer. I also conducted my own research. Several documents indicate that “dSpacer is used to introduce a stable abasic site”, which implies that “abasic dSpacer” is not equal to “abasic site”. So, it may be more appropriate to translate “abasic dSpacer” as 无碱基间隔基. I will also put (dSpacer) after 无碱基间隔基 to distinguish it from ordinary spacers. Thank you all so much for your time and help!

4 KudoZ points were awarded for this answer



Summary of answers provided
4 +2无碱基位点
Jianming Sun


Discussion entries: 1





  

Answers


48 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
abasic dspacer
无碱基位点


Explanation:
dSpacer据我理解就是无碱基位点. Abasic不加也可以,也有用dSpacer (Abasic site)表示.请见 http://usa.eurogentec.com/code/en/page_02.asp?Page=58 中那个dSpacer是没有含氮的碱基的.


--------------------------------------------------
Note added at 2 hrs 24 mins (2005-10-07 02:29:29 GMT)
--------------------------------------------------

谢谢信任！我对这方面也没有什么特别的研究。只是据我知道，这里所谓位点是核酸链中的一个核苷酸位点。SPACER实际上就是基因间没有什么生物作用的核酸片段。核苷酸为核酸的基本单位，由氮碱、核糖和磷酸构成。从我上面给出的链接中的图可看到除DSPACER以外的SPACER都是由几个核苷酸组成的。而这个DSPACER特殊，只有一个位点，没有氮碱，甚至没有磷酸化（这可能也是显示其结构图的原因），故不能称之为核苷酸位点或核苷位点。也可能在核酸链中有的基因之间只有这么一个DSPACER，使它们之间有间隔。我不是专门研究这一方面的，现在也比较忙，有偏差之处，请指教。你也可以译作“无碱基间隔”，或后面再加上一个括号内说明这是“无碱基位点”
。仅供参考。


--------------------------------------------------
Note added at 4 hrs 20 mins (2005-10-07 04:25:05 GMT)
--------------------------------------------------

Hi Yueyin, I guess the "d" might mean"deformed" .

--------------------------------------------------
Note added at 2005-10-08 03:32:18 (GMT)
--------------------------------------------------

I noticed \"non-nucleotidic linker\" in your context, which is exactly what I meant in my explanation for \"这个DSPACER特殊，只有一个位点，没有氮碱，甚至没有磷酸化（这可能也是显示其结构图的原因），故不能称之为核苷酸位点或核苷位点\". From your context, the dSPACER is not singly between gerns. Rather, it is among the sequence of SPACERs, which are 0 to 12 nucleotides long. I am sorry for not reading your context carefully.

Jianming Sun
Local time: 13:16
Specializes in field
Native speaker of: Native in ChineseChinese
PRO pts in category: 23
Grading comment
Jianming,

The link and explanations you provided did help me get a better understanding about dSpacer. I also conducted my own research. Several documents indicate that “dSpacer is used to introduce a stable abasic site”, which implies that “abasic dSpacer” is not equal to “abasic site”. So, it may be more appropriate to translate “abasic dSpacer” as 无碱基间隔基. I will also put (dSpacer) after 无碱基间隔基 to distinguish it from ordinary spacers. Thank you all so much for your time and help!

Peer comments on this answer (and responses from the answerer)
agree  Chinoise
8 mins
  -> Thanks!
agree  melody9999: thanks
1 hr
  -> Thanks!
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

Return to KudoZ list

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.

See also:
ProZ.com term search
Search millions of term translations
Close search
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search